Rainbow of KIBOU (ROK) study

a Breast Cancer Survivor Cohort in Japan

Yuri Mizota, Yasuo Ohashi, Takuji Iwase, Hiroji Iwata, Masataka Sawaki, Takayuki Kinoshita, Naruto Taira, Hirofumi Mukai, Seiichiro Yamamoto

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Although there are a large number of epidemiological studies investigating the etiological role of lifestyle factors in breast cancer, there are few studies on the association between lifestyle factors and breast cancer prognosis. To investigate the influence of lifestyle factors such as diet and physical activity, use of complementary and alternative medicine, and psychosocial factors on prognosis, we designed a large-scale cohort study of female breast cancer patients in Japan. Methods: The planned sample size is 7200. The cohort is being conducted in collaboration with several clinical trials, a cancer registry, and daily practice. Information on clinical factors, treatment, and follow-up will be obtained from the clinical trials and participating hospitals. A self-administered questionnaire is given to subjects before, immediately after, or 1 to 5 years after surgery. Blood and tissue samples are also collected. The primary endpoint is disease-free survival. The secondary endpoints are overall survival and health-related quality of life. The follow-up period will be at least 5 years after the last participant is enrolled. Recruitment began in November 2007. Current status: As of April 2017, there are 5852 patients enrolled in the study along with 1430 biological samples and the study is still ongoing. The number of subjects enrolled in the study is already the largest in the world. Conclusions: The ROK study will provide much important evidence for breast cancer survivorship.

Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalBreast Cancer
DOIs
Publication statusAccepted/In press - May 25 2017

Fingerprint

Survivors
Japan
Breast Neoplasms
Life Style
Complementary Therapies
Clinical Trials
Sample Size
Disease-Free Survival
Registries
Epidemiologic Studies
Cohort Studies
Survival Rate
Quality of Life
Exercise
Psychology
Diet
Survival
Neoplasms
Therapeutics

Keywords

  • Breast cancer
  • Lifestyle
  • Patient cohort
  • Psychosocial factor
  • Survivorship

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Pharmacology (medical)

Cite this

Mizota, Y., Ohashi, Y., Iwase, T., Iwata, H., Sawaki, M., Kinoshita, T., ... Yamamoto, S. (Accepted/In press). Rainbow of KIBOU (ROK) study: a Breast Cancer Survivor Cohort in Japan. Breast Cancer, 1-8. https://doi.org/10.1007/s12282-017-0784-x

Rainbow of KIBOU (ROK) study : a Breast Cancer Survivor Cohort in Japan. / Mizota, Yuri; Ohashi, Yasuo; Iwase, Takuji; Iwata, Hiroji; Sawaki, Masataka; Kinoshita, Takayuki; Taira, Naruto; Mukai, Hirofumi; Yamamoto, Seiichiro.

In: Breast Cancer, 25.05.2017, p. 1-8.

Research output: Contribution to journalArticle

Mizota, Y, Ohashi, Y, Iwase, T, Iwata, H, Sawaki, M, Kinoshita, T, Taira, N, Mukai, H & Yamamoto, S 2017, 'Rainbow of KIBOU (ROK) study: a Breast Cancer Survivor Cohort in Japan', Breast Cancer, pp. 1-8. https://doi.org/10.1007/s12282-017-0784-x
Mizota Y, Ohashi Y, Iwase T, Iwata H, Sawaki M, Kinoshita T et al. Rainbow of KIBOU (ROK) study: a Breast Cancer Survivor Cohort in Japan. Breast Cancer. 2017 May 25;1-8. https://doi.org/10.1007/s12282-017-0784-x
Mizota, Yuri ; Ohashi, Yasuo ; Iwase, Takuji ; Iwata, Hiroji ; Sawaki, Masataka ; Kinoshita, Takayuki ; Taira, Naruto ; Mukai, Hirofumi ; Yamamoto, Seiichiro. / Rainbow of KIBOU (ROK) study : a Breast Cancer Survivor Cohort in Japan. In: Breast Cancer. 2017 ; pp. 1-8.
@article{f141f348f437478db892fff1a8c6bb65,
title = "Rainbow of KIBOU (ROK) study: a Breast Cancer Survivor Cohort in Japan",
abstract = "Background: Although there are a large number of epidemiological studies investigating the etiological role of lifestyle factors in breast cancer, there are few studies on the association between lifestyle factors and breast cancer prognosis. To investigate the influence of lifestyle factors such as diet and physical activity, use of complementary and alternative medicine, and psychosocial factors on prognosis, we designed a large-scale cohort study of female breast cancer patients in Japan. Methods: The planned sample size is 7200. The cohort is being conducted in collaboration with several clinical trials, a cancer registry, and daily practice. Information on clinical factors, treatment, and follow-up will be obtained from the clinical trials and participating hospitals. A self-administered questionnaire is given to subjects before, immediately after, or 1 to 5 years after surgery. Blood and tissue samples are also collected. The primary endpoint is disease-free survival. The secondary endpoints are overall survival and health-related quality of life. The follow-up period will be at least 5 years after the last participant is enrolled. Recruitment began in November 2007. Current status: As of April 2017, there are 5852 patients enrolled in the study along with 1430 biological samples and the study is still ongoing. The number of subjects enrolled in the study is already the largest in the world. Conclusions: The ROK study will provide much important evidence for breast cancer survivorship.",
keywords = "Breast cancer, Lifestyle, Patient cohort, Psychosocial factor, Survivorship",
author = "Yuri Mizota and Yasuo Ohashi and Takuji Iwase and Hiroji Iwata and Masataka Sawaki and Takayuki Kinoshita and Naruto Taira and Hirofumi Mukai and Seiichiro Yamamoto",
year = "2017",
month = "5",
day = "25",
doi = "10.1007/s12282-017-0784-x",
language = "English",
pages = "1--8",
journal = "Breast Cancer",
issn = "1340-6868",
publisher = "Springer Japan",

}

TY - JOUR

T1 - Rainbow of KIBOU (ROK) study

T2 - a Breast Cancer Survivor Cohort in Japan

AU - Mizota, Yuri

AU - Ohashi, Yasuo

AU - Iwase, Takuji

AU - Iwata, Hiroji

AU - Sawaki, Masataka

AU - Kinoshita, Takayuki

AU - Taira, Naruto

AU - Mukai, Hirofumi

AU - Yamamoto, Seiichiro

PY - 2017/5/25

Y1 - 2017/5/25

N2 - Background: Although there are a large number of epidemiological studies investigating the etiological role of lifestyle factors in breast cancer, there are few studies on the association between lifestyle factors and breast cancer prognosis. To investigate the influence of lifestyle factors such as diet and physical activity, use of complementary and alternative medicine, and psychosocial factors on prognosis, we designed a large-scale cohort study of female breast cancer patients in Japan. Methods: The planned sample size is 7200. The cohort is being conducted in collaboration with several clinical trials, a cancer registry, and daily practice. Information on clinical factors, treatment, and follow-up will be obtained from the clinical trials and participating hospitals. A self-administered questionnaire is given to subjects before, immediately after, or 1 to 5 years after surgery. Blood and tissue samples are also collected. The primary endpoint is disease-free survival. The secondary endpoints are overall survival and health-related quality of life. The follow-up period will be at least 5 years after the last participant is enrolled. Recruitment began in November 2007. Current status: As of April 2017, there are 5852 patients enrolled in the study along with 1430 biological samples and the study is still ongoing. The number of subjects enrolled in the study is already the largest in the world. Conclusions: The ROK study will provide much important evidence for breast cancer survivorship.

AB - Background: Although there are a large number of epidemiological studies investigating the etiological role of lifestyle factors in breast cancer, there are few studies on the association between lifestyle factors and breast cancer prognosis. To investigate the influence of lifestyle factors such as diet and physical activity, use of complementary and alternative medicine, and psychosocial factors on prognosis, we designed a large-scale cohort study of female breast cancer patients in Japan. Methods: The planned sample size is 7200. The cohort is being conducted in collaboration with several clinical trials, a cancer registry, and daily practice. Information on clinical factors, treatment, and follow-up will be obtained from the clinical trials and participating hospitals. A self-administered questionnaire is given to subjects before, immediately after, or 1 to 5 years after surgery. Blood and tissue samples are also collected. The primary endpoint is disease-free survival. The secondary endpoints are overall survival and health-related quality of life. The follow-up period will be at least 5 years after the last participant is enrolled. Recruitment began in November 2007. Current status: As of April 2017, there are 5852 patients enrolled in the study along with 1430 biological samples and the study is still ongoing. The number of subjects enrolled in the study is already the largest in the world. Conclusions: The ROK study will provide much important evidence for breast cancer survivorship.

KW - Breast cancer

KW - Lifestyle

KW - Patient cohort

KW - Psychosocial factor

KW - Survivorship

UR - http://www.scopus.com/inward/record.url?scp=85019699884&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85019699884&partnerID=8YFLogxK

U2 - 10.1007/s12282-017-0784-x

DO - 10.1007/s12282-017-0784-x

M3 - Article

SP - 1

EP - 8

JO - Breast Cancer

JF - Breast Cancer

SN - 1340-6868

ER -