Radiofrequency Ablation of Small Lung Metastases by a Single Application of a 2-cm Expandable Electrode

Determination of Favorable Responders

Jun Sakurai, Takao Hiraki, Hidefumi Mimura, Hideo Gobara, Hiroyasu Fujiwara, Nobuhisa Tajiri, Yoshifumi Sano, Susumu Kanazawa

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Purpose: To determine which lung metastases are most likely to be treated effectively with a single radiofrequency (RF) application (defined as two separate applications of RF energy at a single electrode position) with a multitined expandable electrode with arrays 2 cm in diameter. Materials and Methods: The authors retrospectively evaluated 88 lung metastases (mean long-axis diameter, 0.9 cm) in 36 patients (20 men and 16 women; mean age, 57 years) treated with a single RF application with a multitined expandable electrode with arrays 2 cm in diameter. Based on follow-up computed tomographic examinations, the technique effectiveness rates were estimated with Kaplan-Meier analysis. Multiple variables were analyzed with the log-rank test to determine risk factors for local progression. Then, the technique effectiveness rates were again estimated when considering only metastases without risk factors and compared with those of other tumors. Results: The median follow-up period was 13.2 months (range, 6.0-24.7 months). Tumor size greater than 1.0 cm (P = .033) and contact with the bronchus with an inner diameter of at least 2 mm (P = .047) were the significant risk factors for local progression. The technique effectiveness rates for metastases 1.0 cm or smaller that were not in contact with the bronchus (n = 59) were 96% at 1 year and at 2 years; those rates were significantly (P = .010) higher than those in other tumors (n = 29). Conclusions: A single RF application with a multitined expandable electrode with arrays 2 cm in diameter is most likely to suffice in small (≤1 cm) lung metastases not in contact with a bronchus.

Original languageEnglish
Pages (from-to)231-236
Number of pages6
JournalJournal of Vascular and Interventional Radiology
Volume21
Issue number2
DOIs
Publication statusPublished - Feb 2010

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Electrodes
Neoplasm Metastasis
Bronchi
Lung
Neoplasms
Kaplan-Meier Estimate

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Radiofrequency Ablation of Small Lung Metastases by a Single Application of a 2-cm Expandable Electrode : Determination of Favorable Responders. / Sakurai, Jun; Hiraki, Takao; Mimura, Hidefumi; Gobara, Hideo; Fujiwara, Hiroyasu; Tajiri, Nobuhisa; Sano, Yoshifumi; Kanazawa, Susumu.

In: Journal of Vascular and Interventional Radiology, Vol. 21, No. 2, 02.2010, p. 231-236.

Research output: Contribution to journalArticle

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