Radical hydroxyalkylation of C-H bond adjacent to nitrogen of tertiary amides, ureas, and amines

Takehiko Yoshimitsu, Yoshimasa Arano, Hiroto Nagaoka

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Tertiary amides, ureas, and amines undergo direct intermolecular addition to aldehydes under the Et3B/air conditions, thereby providing a unique and simple means for the radical sp3 C-H transformation of nitrogen-containing molecules.

Original languageEnglish
Pages (from-to)11610-11611
Number of pages2
JournalJournal of the American Chemical Society
Volume127
Issue number33
DOIs
Publication statusPublished - Aug 24 2005
Externally publishedYes

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Aldehydes
Amides
Urea
Amines
Nitrogen
Air
Molecules

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Radical hydroxyalkylation of C-H bond adjacent to nitrogen of tertiary amides, ureas, and amines. / Yoshimitsu, Takehiko; Arano, Yoshimasa; Nagaoka, Hiroto.

In: Journal of the American Chemical Society, Vol. 127, No. 33, 24.08.2005, p. 11610-11611.

Research output: Contribution to journalArticle

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