### Abstract

We constructed a precision mathematical model for quantitative evaluation of the micro-dynamics of cultured cells measured with ECIS (Electrical Cell-substrate Impedance Sensing) system that could separately estimate cell-to-cell distance and cell-to-substrate distance. For wide applications of this method, we constructed mathematical models describing for some kinds of cell and some kinds of confluent conditions. The mathematical models of these impedances could be fit well especially from 1 kHz to 10 kHz, which were most interesting frequency range for micro-dynamic analysis in ECIS methods.

Original language | English |
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Title of host publication | Proceedings of 2006 International Conference on Microtechnologies in Medicine and Biology |

Pages | 23-26 |

Number of pages | 4 |

DOIs | |

Publication status | Published - 2006 |

Event | 2006 International Conference on Microtechnologies in Medicine and Biology - Okinawa, Japan Duration: May 9 2006 → May 12 2006 |

### Other

Other | 2006 International Conference on Microtechnologies in Medicine and Biology |
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Country | Japan |

City | Okinawa |

Period | 5/9/06 → 5/12/06 |

### Fingerprint

### Keywords

- Cell culture
- ECIS
- Mathematical model

### ASJC Scopus subject areas

- Biomedical Engineering
- Electrical and Electronic Engineering
- Medicine(all)

### Cite this

*Proceedings of 2006 International Conference on Microtechnologies in Medicine and Biology*(pp. 23-26). [4281298] https://doi.org/10.1109/MMB.2006.251480

**Quantitative evaluation of micro-motion of vascular endothelial cells in Electrical Cell-substrate Impedance Sensing (ECIS) method using a precision mathematical model.** / Goda, Noriko; Yamamoto, Yoshitake; Nakamura, Takao; Kusuhara, Toshimasa; Mohri, Satoshi; Kataoka, Noriyuki; Kajiya, Fumihiko.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

*Proceedings of 2006 International Conference on Microtechnologies in Medicine and Biology.*, 4281298, pp. 23-26, 2006 International Conference on Microtechnologies in Medicine and Biology, Okinawa, Japan, 5/9/06. https://doi.org/10.1109/MMB.2006.251480

}

TY - GEN

T1 - Quantitative evaluation of micro-motion of vascular endothelial cells in Electrical Cell-substrate Impedance Sensing (ECIS) method using a precision mathematical model

AU - Goda, Noriko

AU - Yamamoto, Yoshitake

AU - Nakamura, Takao

AU - Kusuhara, Toshimasa

AU - Mohri, Satoshi

AU - Kataoka, Noriyuki

AU - Kajiya, Fumihiko

PY - 2006

Y1 - 2006

N2 - We constructed a precision mathematical model for quantitative evaluation of the micro-dynamics of cultured cells measured with ECIS (Electrical Cell-substrate Impedance Sensing) system that could separately estimate cell-to-cell distance and cell-to-substrate distance. For wide applications of this method, we constructed mathematical models describing for some kinds of cell and some kinds of confluent conditions. The mathematical models of these impedances could be fit well especially from 1 kHz to 10 kHz, which were most interesting frequency range for micro-dynamic analysis in ECIS methods.

AB - We constructed a precision mathematical model for quantitative evaluation of the micro-dynamics of cultured cells measured with ECIS (Electrical Cell-substrate Impedance Sensing) system that could separately estimate cell-to-cell distance and cell-to-substrate distance. For wide applications of this method, we constructed mathematical models describing for some kinds of cell and some kinds of confluent conditions. The mathematical models of these impedances could be fit well especially from 1 kHz to 10 kHz, which were most interesting frequency range for micro-dynamic analysis in ECIS methods.

KW - Cell culture

KW - ECIS

KW - Mathematical model

UR - http://www.scopus.com/inward/record.url?scp=35548963931&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35548963931&partnerID=8YFLogxK

U2 - 10.1109/MMB.2006.251480

DO - 10.1109/MMB.2006.251480

M3 - Conference contribution

AN - SCOPUS:35548963931

SN - 1424403383

SN - 9781424403387

SP - 23

EP - 26

BT - Proceedings of 2006 International Conference on Microtechnologies in Medicine and Biology

ER -