Quantitative evaluation of micro-motion of vascular endothelial cells in Electrical Cell-substrate Impedance Sensing (ECIS) method using a precision mathematical model

Noriko Goda, Yoshitake Yamamoto, Takao Nakamura, Toshimasa Kusuhara, Satoshi Mohri, Noriyuki Kataoka, Fumihiko Kajiya

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

We constructed a precision mathematical model for quantitative evaluation of the micro-dynamics of cultured cells measured with ECIS (Electrical Cell-substrate Impedance Sensing) system that could separately estimate cell-to-cell distance and cell-to-substrate distance. For wide applications of this method, we constructed mathematical models describing for some kinds of cell and some kinds of confluent conditions. The mathematical models of these impedances could be fit well especially from 1 kHz to 10 kHz, which were most interesting frequency range for micro-dynamic analysis in ECIS methods.

Original languageEnglish
Title of host publicationProceedings of 2006 International Conference on Microtechnologies in Medicine and Biology
Pages23-26
Number of pages4
DOIs
Publication statusPublished - Dec 1 2006
Event2006 International Conference on Microtechnologies in Medicine and Biology - Okinawa, Japan
Duration: May 9 2006May 12 2006

Publication series

NameProceedings of 2006 International Conference on Microtechnologies in Medicine and Biology

Other

Other2006 International Conference on Microtechnologies in Medicine and Biology
CountryJapan
CityOkinawa
Period5/9/065/12/06

Keywords

  • Cell culture
  • ECIS
  • Mathematical model

ASJC Scopus subject areas

  • Biomedical Engineering
  • Electrical and Electronic Engineering
  • Medicine(all)

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    Goda, N., Yamamoto, Y., Nakamura, T., Kusuhara, T., Mohri, S., Kataoka, N., & Kajiya, F. (2006). Quantitative evaluation of micro-motion of vascular endothelial cells in Electrical Cell-substrate Impedance Sensing (ECIS) method using a precision mathematical model. In Proceedings of 2006 International Conference on Microtechnologies in Medicine and Biology (pp. 23-26). [4281298] (Proceedings of 2006 International Conference on Microtechnologies in Medicine and Biology). https://doi.org/10.1109/MMB.2006.251480