Quantitative analysis of a cross-sectional area of the optic nerve: A comparison between albino and pigmented rats

T. Sugimoto, Y. Fukuda, K. Wakakuwa

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Comparative studies were made on albino and gray rats by measuring several morphological characteristics seen in cross-sections of the optic nerve. The total cross-sectional area of the optic nerve was about 30% smaller in the albino than in the gray rat, while the fiber density was 1.4 times higher in the albino than in the gray rat. The estimated total fiber count was about the same in the two strains: around 100,000 to 110,000 fibers. Except for a few unmyelinated fibers (less than 1%) all fibers were myelinated. Axon diameters of the optic nerve fibers were distributed in smaller values for the albino than for the gray rat, though the overall diameter range was similar (0.2-3.0 μm). The myelin sheath was also thinner in the albino than in the gray rat.

Original languageEnglish
Pages (from-to)266-274
Number of pages9
JournalExperimental Brain Research
Volume54
Issue number2
DOIs
Publication statusPublished - Mar 1984
Externally publishedYes

Fingerprint

Optic Nerve
Cross-Sectional Studies
Myelin Sheath
Nerve Fibers
Axons

Keywords

  • Albino and gray rats
  • Axon diameter
  • Fiber count
  • Myelin sheath thickness
  • Optic nerve

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Quantitative analysis of a cross-sectional area of the optic nerve : A comparison between albino and pigmented rats. / Sugimoto, T.; Fukuda, Y.; Wakakuwa, K.

In: Experimental Brain Research, Vol. 54, No. 2, 03.1984, p. 266-274.

Research output: Contribution to journalArticle

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