Quantitation of DNA damage by an aldehyde reactive probe (ARP).

S. Kurisu, T. Miya, Hiroaki Terato, A. Masaoka, Y. Ohyama, K. Kubo, H. Ide

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

DNA is constantly damaged by endogenous and environmental agents. Abasic sites representing a major class of DNA damage can be quantitated by an ELISA-like assay using an aldehyde reactive probe (ARP). It is shown that oxidative pyrimidine lesions can be also quantitated by the ARP assay in combination with the treatment with endonuclease III.

Original languageEnglish
Pages (from-to)45-46
Number of pages2
JournalNucleic acids research. Supplement (2001)
Issue number1
DOIs
Publication statusPublished - Jan 1 2001
Externally publishedYes

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DNA Damage
Endonucleases
Enzyme-Linked Immunosorbent Assay
DNA
DNA-aldehydes
O-(biotinylcarbazoylmethyl)hydroxylamine
Therapeutics
pyrimidine

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Quantitation of DNA damage by an aldehyde reactive probe (ARP). / Kurisu, S.; Miya, T.; Terato, Hiroaki; Masaoka, A.; Ohyama, Y.; Kubo, K.; Ide, H.

In: Nucleic acids research. Supplement (2001), No. 1, 01.01.2001, p. 45-46.

Research output: Contribution to journalArticle

Kurisu, S. ; Miya, T. ; Terato, Hiroaki ; Masaoka, A. ; Ohyama, Y. ; Kubo, K. ; Ide, H. / Quantitation of DNA damage by an aldehyde reactive probe (ARP). In: Nucleic acids research. Supplement (2001). 2001 ; No. 1. pp. 45-46.
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