Qt dispersion measured by automatic computerized 12-lead electrocardiography contributes significantly to detection of left ventricular hypertrophy in Japanese patients

R. Izumi, Ryouko Shinohata, N. Ohmaru, T. Kitawaki, Shinichi Usui, S. Ikeda, S. Kusachi

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1 Citation (Scopus)

Abstract

This study assessed the diagnostic value of QT dispersion for left ventricular hypertrophy (LVH) as determined by echocardiography. The QT and QRS interval parameters were determined automatically using computerized 12-lead electrocardiography in 153 Japanese out- patients. Corrected QT dispersion (QTcD) and maximal QRS duration (MaxQRS) were significantly correlated with left ventricular mass index. The sum of QTcD and MaxQRS showed the highest correlation with left ventricular mass index among QT and QRS interval parameters and their combinations. The cut-off points for LVH discrimination in this study were different to those reported in Western, mainly Caucasian, populations, suggesting the need for ethnicity-specific LVH detection criteria. A scoring system derived from multiple logistic regression analysis, employing a combination of QTcD, QRS time-voltage product and ST-T change, showed a specificity of 86.3%. It was concluded that QTcD, in addition to QRS time-voltage product and ST-T change, improved the detection of LVH.

Original languageEnglish
Pages (from-to)51-63
Number of pages13
JournalJournal of International Medical Research
Volume39
Issue number1
Publication statusPublished - 2011

Fingerprint

Left Ventricular Hypertrophy
Electrocardiography
Echocardiography
Electric potential
Regression analysis
Logistics
Outpatients
Logistic Models
Regression Analysis
Lead
Population

Keywords

  • Echocardiography
  • Electrocardiogram
  • Left ventricular hypertrophy
  • Left ventricular mass
  • QT dispersion
  • Receiver operating characteristic curve

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry
  • Cell Biology
  • Biochemistry, medical

Cite this

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title = "Qt dispersion measured by automatic computerized 12-lead electrocardiography contributes significantly to detection of left ventricular hypertrophy in Japanese patients",
abstract = "This study assessed the diagnostic value of QT dispersion for left ventricular hypertrophy (LVH) as determined by echocardiography. The QT and QRS interval parameters were determined automatically using computerized 12-lead electrocardiography in 153 Japanese out- patients. Corrected QT dispersion (QTcD) and maximal QRS duration (MaxQRS) were significantly correlated with left ventricular mass index. The sum of QTcD and MaxQRS showed the highest correlation with left ventricular mass index among QT and QRS interval parameters and their combinations. The cut-off points for LVH discrimination in this study were different to those reported in Western, mainly Caucasian, populations, suggesting the need for ethnicity-specific LVH detection criteria. A scoring system derived from multiple logistic regression analysis, employing a combination of QTcD, QRS time-voltage product and ST-T change, showed a specificity of 86.3{\%}. It was concluded that QTcD, in addition to QRS time-voltage product and ST-T change, improved the detection of LVH.",
keywords = "Echocardiography, Electrocardiogram, Left ventricular hypertrophy, Left ventricular mass, QT dispersion, Receiver operating characteristic curve",
author = "R. Izumi and Ryouko Shinohata and N. Ohmaru and T. Kitawaki and Shinichi Usui and S. Ikeda and S. Kusachi",
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T1 - Qt dispersion measured by automatic computerized 12-lead electrocardiography contributes significantly to detection of left ventricular hypertrophy in Japanese patients

AU - Izumi, R.

AU - Shinohata, Ryouko

AU - Ohmaru, N.

AU - Kitawaki, T.

AU - Usui, Shinichi

AU - Ikeda, S.

AU - Kusachi, S.

PY - 2011

Y1 - 2011

N2 - This study assessed the diagnostic value of QT dispersion for left ventricular hypertrophy (LVH) as determined by echocardiography. The QT and QRS interval parameters were determined automatically using computerized 12-lead electrocardiography in 153 Japanese out- patients. Corrected QT dispersion (QTcD) and maximal QRS duration (MaxQRS) were significantly correlated with left ventricular mass index. The sum of QTcD and MaxQRS showed the highest correlation with left ventricular mass index among QT and QRS interval parameters and their combinations. The cut-off points for LVH discrimination in this study were different to those reported in Western, mainly Caucasian, populations, suggesting the need for ethnicity-specific LVH detection criteria. A scoring system derived from multiple logistic regression analysis, employing a combination of QTcD, QRS time-voltage product and ST-T change, showed a specificity of 86.3%. It was concluded that QTcD, in addition to QRS time-voltage product and ST-T change, improved the detection of LVH.

AB - This study assessed the diagnostic value of QT dispersion for left ventricular hypertrophy (LVH) as determined by echocardiography. The QT and QRS interval parameters were determined automatically using computerized 12-lead electrocardiography in 153 Japanese out- patients. Corrected QT dispersion (QTcD) and maximal QRS duration (MaxQRS) were significantly correlated with left ventricular mass index. The sum of QTcD and MaxQRS showed the highest correlation with left ventricular mass index among QT and QRS interval parameters and their combinations. The cut-off points for LVH discrimination in this study were different to those reported in Western, mainly Caucasian, populations, suggesting the need for ethnicity-specific LVH detection criteria. A scoring system derived from multiple logistic regression analysis, employing a combination of QTcD, QRS time-voltage product and ST-T change, showed a specificity of 86.3%. It was concluded that QTcD, in addition to QRS time-voltage product and ST-T change, improved the detection of LVH.

KW - Echocardiography

KW - Electrocardiogram

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KW - Left ventricular mass

KW - QT dispersion

KW - Receiver operating characteristic curve

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