Pulsion severity showed a good correlation with cognitive function in Parkinson’s disease

Tomoko Kurata, Noriko Hatanaka, Nobutoshi Morimoto, Shoko Deguchi, Kentaro Deguchi, Yoshio Ikeda, Koji Abe

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objectives: To examine the correlation between cognitive impairment and postural instability in Parkinson’s disease (PD) patients by using posturography.

Methods: We investigated 88 PD patients comparing clinical scorings of cognitive functions and pulsion severity, and quantitative measurement of postural instability by posturography with the length of the center of gravity (LNG) and envelope area (ENV).

Results: The number of patients with severe pulsion increased in PD with disease progression assessed by Hoehn and Yahr (H & Y) scale regardless of age, and a significant correlation was observed between the pulsion severity and both LNG (R = 0.4242) and ENV (R = 0.4335). Both LNG and ENV showed a good correlation with all cognitive assessments such as mini-mental state examination (MMSE), Montreal cognitive assessment (MoCA), and frontal assessment battery (FAB), suggesting that cognitive impairment became worse with the longer LNG and the larger ENV. Among the cognitive assessments, MoCA showed the highest correlation (R = 0.56-0.62) with both LNG and ENV, reflecting that MoCA is the most sensitive and reliable screening for dementia in PD.

Discussion: The present study showed that posturography is useful to quantify the pulsion severity in PD patients, that pulsion severity and cognitive function showed a good correlation especially assessed by MoCA, and that posturography thus provides a more detailed quantitative correlation of postural instability to cognitive impairment.

Original languageEnglish
Pages (from-to)962-967
Number of pages6
JournalNeurological Research
Volume36
Issue number11
DOIs
Publication statusPublished - Nov 1 2014

Fingerprint

Gravitation
Cognition
Parkinson Disease
Dementia
Disease Progression
Cognitive Dysfunction

Keywords

  • Cognitive impairment
  • Parkinson’s disease
  • Postural instability
  • Posturography
  • Pulsion

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Medicine(all)

Cite this

Pulsion severity showed a good correlation with cognitive function in Parkinson’s disease. / Kurata, Tomoko; Hatanaka, Noriko; Morimoto, Nobutoshi; Deguchi, Shoko; Deguchi, Kentaro; Ikeda, Yoshio; Abe, Koji.

In: Neurological Research, Vol. 36, No. 11, 01.11.2014, p. 962-967.

Research output: Contribution to journalArticle

Kurata, T, Hatanaka, N, Morimoto, N, Deguchi, S, Deguchi, K, Ikeda, Y & Abe, K 2014, 'Pulsion severity showed a good correlation with cognitive function in Parkinson’s disease', Neurological Research, vol. 36, no. 11, pp. 962-967. https://doi.org/10.1179/1743132814Y.0000000384
Kurata, Tomoko ; Hatanaka, Noriko ; Morimoto, Nobutoshi ; Deguchi, Shoko ; Deguchi, Kentaro ; Ikeda, Yoshio ; Abe, Koji. / Pulsion severity showed a good correlation with cognitive function in Parkinson’s disease. In: Neurological Research. 2014 ; Vol. 36, No. 11. pp. 962-967.
@article{9597294da6f4476aa56d44e32960e098,
title = "Pulsion severity showed a good correlation with cognitive function in Parkinson’s disease",
abstract = "Objectives: To examine the correlation between cognitive impairment and postural instability in Parkinson’s disease (PD) patients by using posturography.Methods: We investigated 88 PD patients comparing clinical scorings of cognitive functions and pulsion severity, and quantitative measurement of postural instability by posturography with the length of the center of gravity (LNG) and envelope area (ENV).Results: The number of patients with severe pulsion increased in PD with disease progression assessed by Hoehn and Yahr (H & Y) scale regardless of age, and a significant correlation was observed between the pulsion severity and both LNG (R = 0.4242) and ENV (R = 0.4335). Both LNG and ENV showed a good correlation with all cognitive assessments such as mini-mental state examination (MMSE), Montreal cognitive assessment (MoCA), and frontal assessment battery (FAB), suggesting that cognitive impairment became worse with the longer LNG and the larger ENV. Among the cognitive assessments, MoCA showed the highest correlation (R = 0.56-0.62) with both LNG and ENV, reflecting that MoCA is the most sensitive and reliable screening for dementia in PD.Discussion: The present study showed that posturography is useful to quantify the pulsion severity in PD patients, that pulsion severity and cognitive function showed a good correlation especially assessed by MoCA, and that posturography thus provides a more detailed quantitative correlation of postural instability to cognitive impairment.",
keywords = "Cognitive impairment, Parkinson’s disease, Postural instability, Posturography, Pulsion",
author = "Tomoko Kurata and Noriko Hatanaka and Nobutoshi Morimoto and Shoko Deguchi and Kentaro Deguchi and Yoshio Ikeda and Koji Abe",
year = "2014",
month = "11",
day = "1",
doi = "10.1179/1743132814Y.0000000384",
language = "English",
volume = "36",
pages = "962--967",
journal = "Neurological Research",
issn = "0161-6412",
publisher = "Maney Publishing",
number = "11",

}

TY - JOUR

T1 - Pulsion severity showed a good correlation with cognitive function in Parkinson’s disease

AU - Kurata, Tomoko

AU - Hatanaka, Noriko

AU - Morimoto, Nobutoshi

AU - Deguchi, Shoko

AU - Deguchi, Kentaro

AU - Ikeda, Yoshio

AU - Abe, Koji

PY - 2014/11/1

Y1 - 2014/11/1

N2 - Objectives: To examine the correlation between cognitive impairment and postural instability in Parkinson’s disease (PD) patients by using posturography.Methods: We investigated 88 PD patients comparing clinical scorings of cognitive functions and pulsion severity, and quantitative measurement of postural instability by posturography with the length of the center of gravity (LNG) and envelope area (ENV).Results: The number of patients with severe pulsion increased in PD with disease progression assessed by Hoehn and Yahr (H & Y) scale regardless of age, and a significant correlation was observed between the pulsion severity and both LNG (R = 0.4242) and ENV (R = 0.4335). Both LNG and ENV showed a good correlation with all cognitive assessments such as mini-mental state examination (MMSE), Montreal cognitive assessment (MoCA), and frontal assessment battery (FAB), suggesting that cognitive impairment became worse with the longer LNG and the larger ENV. Among the cognitive assessments, MoCA showed the highest correlation (R = 0.56-0.62) with both LNG and ENV, reflecting that MoCA is the most sensitive and reliable screening for dementia in PD.Discussion: The present study showed that posturography is useful to quantify the pulsion severity in PD patients, that pulsion severity and cognitive function showed a good correlation especially assessed by MoCA, and that posturography thus provides a more detailed quantitative correlation of postural instability to cognitive impairment.

AB - Objectives: To examine the correlation between cognitive impairment and postural instability in Parkinson’s disease (PD) patients by using posturography.Methods: We investigated 88 PD patients comparing clinical scorings of cognitive functions and pulsion severity, and quantitative measurement of postural instability by posturography with the length of the center of gravity (LNG) and envelope area (ENV).Results: The number of patients with severe pulsion increased in PD with disease progression assessed by Hoehn and Yahr (H & Y) scale regardless of age, and a significant correlation was observed between the pulsion severity and both LNG (R = 0.4242) and ENV (R = 0.4335). Both LNG and ENV showed a good correlation with all cognitive assessments such as mini-mental state examination (MMSE), Montreal cognitive assessment (MoCA), and frontal assessment battery (FAB), suggesting that cognitive impairment became worse with the longer LNG and the larger ENV. Among the cognitive assessments, MoCA showed the highest correlation (R = 0.56-0.62) with both LNG and ENV, reflecting that MoCA is the most sensitive and reliable screening for dementia in PD.Discussion: The present study showed that posturography is useful to quantify the pulsion severity in PD patients, that pulsion severity and cognitive function showed a good correlation especially assessed by MoCA, and that posturography thus provides a more detailed quantitative correlation of postural instability to cognitive impairment.

KW - Cognitive impairment

KW - Parkinson’s disease

KW - Postural instability

KW - Posturography

KW - Pulsion

UR - http://www.scopus.com/inward/record.url?scp=84918819937&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84918819937&partnerID=8YFLogxK

U2 - 10.1179/1743132814Y.0000000384

DO - 10.1179/1743132814Y.0000000384

M3 - Article

C2 - 24836461

AN - SCOPUS:84918819937

VL - 36

SP - 962

EP - 967

JO - Neurological Research

JF - Neurological Research

SN - 0161-6412

IS - 11

ER -