Pulmonary lymphoma of large B-cell type mimicking Wegener's granulomatosis

Nobuaki Miyahara, Ryosuke Eda, Yoshiki Umemori, Tomoyuki Murakami, Naomi Kunichika, Kiyoshi Makihata, Keisuke Aoe, Kazuo Murakami, Hiroyasu Takeyama, Mine Harada

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

A 27-year-old man with a primary pulmonary lymphoma of large B-cell type is described. Symptoms involved both the upper and lower respiratory tract. A chest roentgenogram showed a dense mass with cavitation. Transbronchial biopsy specimens revealed no atypical cells, rather they demonstrated granulomatous infiltration and vasculitis consistent with but not conclusively diagnostic of Wegener's granulomatosis. The pulmonary mass became smaller after sulfamethoxazole-trimethoprim therapy. These features suggested Wegener's granulomatosis. However, an open biopsy specimen was diagnostic for diffuse lymphoma of large B-cell type. High-grade pulmonary lymphoma should be considered in the differential diagnosis of patients with clinical and pathologic features suggesting Wegener's granulomatosis.

Original languageEnglish
Pages (from-to)786-790
Number of pages5
JournalInternal Medicine
Volume40
Issue number8
Publication statusPublished - Aug 2001

Fingerprint

Granulomatosis with Polyangiitis
B-Cell Lymphoma
Lung
Biopsy
Lymphoma, Large B-Cell, Diffuse
Sulfamethoxazole Drug Combination Trimethoprim
Vasculitis
Respiratory System
Non-Hodgkin's Lymphoma
Differential Diagnosis
Thorax
Therapeutics

Keywords

  • Large-cell type
  • Lung
  • Non-Hodgkin's lymphoma

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Miyahara, N., Eda, R., Umemori, Y., Murakami, T., Kunichika, N., Makihata, K., ... Harada, M. (2001). Pulmonary lymphoma of large B-cell type mimicking Wegener's granulomatosis. Internal Medicine, 40(8), 786-790.

Pulmonary lymphoma of large B-cell type mimicking Wegener's granulomatosis. / Miyahara, Nobuaki; Eda, Ryosuke; Umemori, Yoshiki; Murakami, Tomoyuki; Kunichika, Naomi; Makihata, Kiyoshi; Aoe, Keisuke; Murakami, Kazuo; Takeyama, Hiroyasu; Harada, Mine.

In: Internal Medicine, Vol. 40, No. 8, 08.2001, p. 786-790.

Research output: Contribution to journalArticle

Miyahara, N, Eda, R, Umemori, Y, Murakami, T, Kunichika, N, Makihata, K, Aoe, K, Murakami, K, Takeyama, H & Harada, M 2001, 'Pulmonary lymphoma of large B-cell type mimicking Wegener's granulomatosis', Internal Medicine, vol. 40, no. 8, pp. 786-790.
Miyahara N, Eda R, Umemori Y, Murakami T, Kunichika N, Makihata K et al. Pulmonary lymphoma of large B-cell type mimicking Wegener's granulomatosis. Internal Medicine. 2001 Aug;40(8):786-790.
Miyahara, Nobuaki ; Eda, Ryosuke ; Umemori, Yoshiki ; Murakami, Tomoyuki ; Kunichika, Naomi ; Makihata, Kiyoshi ; Aoe, Keisuke ; Murakami, Kazuo ; Takeyama, Hiroyasu ; Harada, Mine. / Pulmonary lymphoma of large B-cell type mimicking Wegener's granulomatosis. In: Internal Medicine. 2001 ; Vol. 40, No. 8. pp. 786-790.
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