Abstract

An 83-year-old Japanese man underwent esophagogastroduodenoscopy for screening purposes. He had a medical history of hypertension, chronic kidney disease, chronic heart failure, and chronic myeloid leukemia, and he had been taking the following medications: ferrous citrate, furosemide, spironolactone, tolvaptan, bisoprolol, nicorandil, warfarin, nilotinib, febuxostat, esomeprazole, digestive enzyme complex, ambroxol, carbocysteine, and potassium L-aspartate. Esophagogastroduodenoscopy revealed a brownish speckled pigmentation in the duodenal bulb. Biopsy specimens from the duodenal villi revealed a brown pigment deposition, which appeared bright on scanning electron microscopy. Energy dispersive X-ray spectroscopy and elemental mapping revealed the presence of iron and sulfur in the duodenal villi. Consequently, pseudomelanosis duodeni was diagnosed based on these findings.

Original languageEnglish
Pages (from-to)1264-1268
Number of pages5
JournalJournal of Japanese Society of Gastroenterology
Volume114
Issue number7
Publication statusPublished - 2017

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Digestive System Endoscopy
Aspartic Acid
Carbocysteine
Ambroxol
Esomeprazole
Bisoprolol
Nicorandil
X-Ray Emission Spectrometry
Spironolactone
Furosemide
Pigmentation
Warfarin
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Chronic Renal Insufficiency
Sulfur
Electron Scanning Microscopy
Iron
Heart Failure
Hypertension
Biopsy

ASJC Scopus subject areas

  • Gastroenterology

Cite this

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title = "Pseudomelanosis duodeni: A case report",
abstract = "An 83-year-old Japanese man underwent esophagogastroduodenoscopy for screening purposes. He had a medical history of hypertension, chronic kidney disease, chronic heart failure, and chronic myeloid leukemia, and he had been taking the following medications: ferrous citrate, furosemide, spironolactone, tolvaptan, bisoprolol, nicorandil, warfarin, nilotinib, febuxostat, esomeprazole, digestive enzyme complex, ambroxol, carbocysteine, and potassium L-aspartate. Esophagogastroduodenoscopy revealed a brownish speckled pigmentation in the duodenal bulb. Biopsy specimens from the duodenal villi revealed a brown pigment deposition, which appeared bright on scanning electron microscopy. Energy dispersive X-ray spectroscopy and elemental mapping revealed the presence of iron and sulfur in the duodenal villi. Consequently, pseudomelanosis duodeni was diagnosed based on these findings.",
author = "Masaya Iwamuro and Shohei Oka and Hiromitsu Kanzaki and Takehiro Tanaka and Seiji Kawano and Yoshiro Kawahara and Hiroyuki Okada",
year = "2017",
language = "English",
volume = "114",
pages = "1264--1268",
journal = "Japanese Journal of Gastroenterology",
issn = "0446-6586",
publisher = "Japanese Society of Gastroenterology",
number = "7",

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TY - JOUR

T1 - Pseudomelanosis duodeni

T2 - A case report

AU - Iwamuro, Masaya

AU - Oka, Shohei

AU - Kanzaki, Hiromitsu

AU - Tanaka, Takehiro

AU - Kawano, Seiji

AU - Kawahara, Yoshiro

AU - Okada, Hiroyuki

PY - 2017

Y1 - 2017

N2 - An 83-year-old Japanese man underwent esophagogastroduodenoscopy for screening purposes. He had a medical history of hypertension, chronic kidney disease, chronic heart failure, and chronic myeloid leukemia, and he had been taking the following medications: ferrous citrate, furosemide, spironolactone, tolvaptan, bisoprolol, nicorandil, warfarin, nilotinib, febuxostat, esomeprazole, digestive enzyme complex, ambroxol, carbocysteine, and potassium L-aspartate. Esophagogastroduodenoscopy revealed a brownish speckled pigmentation in the duodenal bulb. Biopsy specimens from the duodenal villi revealed a brown pigment deposition, which appeared bright on scanning electron microscopy. Energy dispersive X-ray spectroscopy and elemental mapping revealed the presence of iron and sulfur in the duodenal villi. Consequently, pseudomelanosis duodeni was diagnosed based on these findings.

AB - An 83-year-old Japanese man underwent esophagogastroduodenoscopy for screening purposes. He had a medical history of hypertension, chronic kidney disease, chronic heart failure, and chronic myeloid leukemia, and he had been taking the following medications: ferrous citrate, furosemide, spironolactone, tolvaptan, bisoprolol, nicorandil, warfarin, nilotinib, febuxostat, esomeprazole, digestive enzyme complex, ambroxol, carbocysteine, and potassium L-aspartate. Esophagogastroduodenoscopy revealed a brownish speckled pigmentation in the duodenal bulb. Biopsy specimens from the duodenal villi revealed a brown pigment deposition, which appeared bright on scanning electron microscopy. Energy dispersive X-ray spectroscopy and elemental mapping revealed the presence of iron and sulfur in the duodenal villi. Consequently, pseudomelanosis duodeni was diagnosed based on these findings.

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JF - Japanese Journal of Gastroenterology

SN - 0446-6586

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