Protein tyrosine phosphorylation during phytohormone-stimulated cell proliferation in Arabidopsis hypocotyls

Hao Jen Huang, Yu Mei Lin, Dinq Ding Huang, Takuya Takahashi, Munetaka Sugiyama

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)

Abstract

Very little is known about the molecular events triggering differentiated cells to re-enter the cell cycle. We have investigated the possible role of tyrosine phosphorylation in this process with hypocotyl explants of Arabidopsis thaliana. Phytohormone-stimulated cell cycle reactivation in hypocotyls was accompanied by tyrosine phosphorylation of several proteins. Such regulation of the tyrosine phosphorylation in these proteins was not observed in a callus-formation-deficient mutant, srd2, a result which suggests that the induction of tyrosine phosphorylation occurs as a specific event in callus cell proliferation. The promoter activity of cyclin-dependent kinase, CDKA;1, was also examined in phytohormone-stimulated hypocotyls. This study highlighted that protein tyrosine phosphorylation may play an important regulatory role in phytohormone-stimulated cell proliferation.

Original languageEnglish
Pages (from-to)770-775
Number of pages6
JournalPlant and Cell Physiology
Volume44
Issue number7
DOIs
Publication statusPublished - Jul 1 2003
Externally publishedYes

Keywords

  • Cell proliferation
  • Cyclin-dependent kinase
  • Tyrosine phosphorylation

ASJC Scopus subject areas

  • Physiology
  • Plant Science
  • Cell Biology

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