Protein quality control in chloroplasts: A current model of D1 protein degradation in the photosystem II repair cycle

Yusuke Kato, Wataru Sakamoto

Research output: Contribution to journalReview article

102 Citations (Scopus)

Abstract

The chloroplast originated from endosymbiosis of photosynthetic bacteria. Thus, mechanisms essential for chloroplast biogenesis/homeostasis (protein synthesis, import from cytosol, assembly, and degradation) are predominantly governed by prokaryotic systems. Among these, the quality control system is crucial, because light energy constantly damages photosynthetic proteins and excessive light often limits plant growth by irreversibly inactivating the photosynthetic apparatuses. Here, we overview prokaryotic proteases (FtsH and Deg) which are two enzymes that play critical roles in this system. We particularly focus on Photosystem II (PSII) in thylakoid membranes, which is composed of more than 20 subunits. Among the subunits is one of the intrinsic reaction centre proteins (D1) which is considered to be the target of photodamage. Its rapid and specific turnover suggests that photodamaged D1 is degraded by these proteases and replaced with a de novo synthesized one in a system which is termed the PSII repair cycle. We discuss a current model of D1 degradation which is executed by a concerted action of particular FtsH and Deg isoforms.

Original languageEnglish
Pages (from-to)463-469
Number of pages7
JournalJournal of biochemistry
Volume146
Issue number4
DOIs
Publication statusPublished - Oct 1 2009

Keywords

  • Chloroplast
  • D1 degradation
  • Deg protease
  • FtsH metalloprotease
  • Photosynthesis

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

Fingerprint Dive into the research topics of 'Protein quality control in chloroplasts: A current model of D1 protein degradation in the photosystem II repair cycle'. Together they form a unique fingerprint.

  • Cite this