Protective effect of bifemelane hydrochloride on ischemic hippocampal CA1 neuronal damage in the Gerbil: Relation to induction of HSP70

X. H. Liu, Koji Abe, M. Aoki, T. H. Lee, H. Kato, K. Kogure

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A protective effect of bifemelane hydrochloride (BF) on hippocampal CA1 neuronal death in gerbils was investigated following transient forebrain ischemia in relation to the induction of 70-kd heat shock protein (HSP70) and its mRNA. Histological examination showed that the neuronal density of the hippocampal CA1 sector treated with 10 and 30 mg/kg of BF (i.p.) was higher than that of the vehicle (p

Original languageEnglish
Pages (from-to)161-167
Number of pages7
JournalLife Sciences
Volume53
Issue number2
DOIs
Publication statusPublished - 1993
Externally publishedYes

Fingerprint

HSP70 Heat-Shock Proteins
Gerbillinae
Hippocampal CA1 Region
Prosencephalon
Ischemia
Messenger RNA
bifemelane

ASJC Scopus subject areas

  • Pharmacology

Cite this

Protective effect of bifemelane hydrochloride on ischemic hippocampal CA1 neuronal damage in the Gerbil : Relation to induction of HSP70. / Liu, X. H.; Abe, Koji; Aoki, M.; Lee, T. H.; Kato, H.; Kogure, K.

In: Life Sciences, Vol. 53, No. 2, 1993, p. 161-167.

Research output: Contribution to journalArticle

@article{3c9ff2b16fdd4d7696f4cc99e889cdba,
title = "Protective effect of bifemelane hydrochloride on ischemic hippocampal CA1 neuronal damage in the Gerbil: Relation to induction of HSP70",
abstract = "A protective effect of bifemelane hydrochloride (BF) on hippocampal CA1 neuronal death in gerbils was investigated following transient forebrain ischemia in relation to the induction of 70-kd heat shock protein (HSP70) and its mRNA. Histological examination showed that the neuronal density of the hippocampal CA1 sector treated with 10 and 30 mg/kg of BF (i.p.) was higher than that of the vehicle (p",
author = "Liu, {X. H.} and Koji Abe and M. Aoki and Lee, {T. H.} and H. Kato and K. Kogure",
year = "1993",
doi = "10.1016/0024-3205(93)90663-N",
language = "English",
volume = "53",
pages = "161--167",
journal = "Life Sciences",
issn = "0024-3205",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Protective effect of bifemelane hydrochloride on ischemic hippocampal CA1 neuronal damage in the Gerbil

T2 - Relation to induction of HSP70

AU - Liu, X. H.

AU - Abe, Koji

AU - Aoki, M.

AU - Lee, T. H.

AU - Kato, H.

AU - Kogure, K.

PY - 1993

Y1 - 1993

N2 - A protective effect of bifemelane hydrochloride (BF) on hippocampal CA1 neuronal death in gerbils was investigated following transient forebrain ischemia in relation to the induction of 70-kd heat shock protein (HSP70) and its mRNA. Histological examination showed that the neuronal density of the hippocampal CA1 sector treated with 10 and 30 mg/kg of BF (i.p.) was higher than that of the vehicle (p

AB - A protective effect of bifemelane hydrochloride (BF) on hippocampal CA1 neuronal death in gerbils was investigated following transient forebrain ischemia in relation to the induction of 70-kd heat shock protein (HSP70) and its mRNA. Histological examination showed that the neuronal density of the hippocampal CA1 sector treated with 10 and 30 mg/kg of BF (i.p.) was higher than that of the vehicle (p

UR - http://www.scopus.com/inward/record.url?scp=0027214952&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027214952&partnerID=8YFLogxK

U2 - 10.1016/0024-3205(93)90663-N

DO - 10.1016/0024-3205(93)90663-N

M3 - Article

C2 - 8515688

AN - SCOPUS:0027214952

VL - 53

SP - 161

EP - 167

JO - Life Sciences

JF - Life Sciences

SN - 0024-3205

IS - 2

ER -