Prostate cancer gene therapy

Yasutomo Nasu, Hiromi Kumon

Research output: Contribution to journalArticle

Abstract

With the advance in genetic engineering, tumor biology and immunology, gene therapy has been recognized as a promising new treatment option for cancer including prostate cancer. Several clinical trials of prostate cancer gene therapy are currently underway, using therapeutic genes which include suicide genes, immunomodulatory genes, tumor suppressor genes and anti-oncogenes. Although the gene therapy for prostate cancer as a clinical alternative is still early stage which requires several technological breakthrough, some information obtained from clinical trial indicates full potential of prostate cancer gene therapy. Concordant progress both in the basic research and gene therapy technology will make prostate cancer gene therapy ready for wide scale of practice in the future. In this report, general concept and current progress in prostate cancer gene therapy are summarized.

Original languageEnglish
Pages (from-to)485-490
Number of pages6
JournalNihon rinsho. Japanese journal of clinical medicine
Volume63
Issue number3
Publication statusPublished - 2005

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Neoplasm Genes
Genetic Therapy
Prostatic Neoplasms
Tumor Suppressor Genes
Clinical Trials
Genes
Genetic Engineering
Allergy and Immunology
Suicide
Technology
Therapeutics
Research
Neoplasms

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Prostate cancer gene therapy. / Nasu, Yasutomo; Kumon, Hiromi.

In: Nihon rinsho. Japanese journal of clinical medicine, Vol. 63, No. 3, 2005, p. 485-490.

Research output: Contribution to journalArticle

Nasu, Yasutomo ; Kumon, Hiromi. / Prostate cancer gene therapy. In: Nihon rinsho. Japanese journal of clinical medicine. 2005 ; Vol. 63, No. 3. pp. 485-490.
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