Prostaglandins F2α and E2 in Aqueous Humor of Patients with Cataract Surgery

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

To understand the role of prostaglandins F and E 2 in aqueous humor under the normal condition, their concentrations were measured by enzyme immunoassay in aqueous fluid obtained from either eye of 60 patients during cataract surgery and correlated with clinical factors as the age and intraocular pressure. The concentrations of prostaglandin F in the aqueous of all patients were below the level of detection. The concentrations of prostaglandin E2 in the aqueous were below the level of detection in 37 patients while ranged from 9 to 48 pg/ mL (median, 31) in 23 patients. The levels of prostaglandin E2 did not have correlation with the age of the patients or the intraocular pressure of the eyes. In conclusions, the concentrations of prostaglandin E2 were apparently higher than the concentrations of prostaglandin F in the aqueous. This study could not prove the relationship between prostaglandin levels and the intraocular pressure or the age.

Original languageEnglish
Pages (from-to)101-106
Number of pages6
JournalJournal of Ocular Pharmacology and Therapeutics
Volume20
Issue number2
DOIs
Publication statusPublished - Apr 2004

Fingerprint

Dinoprost
Aqueous Humor
Dinoprostone
Cataract
Intraocular Pressure
Prostaglandins F
Age Factors
Prostaglandins E
Immunoenzyme Techniques
Prostaglandins

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Ophthalmology
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Prostaglandins F2α and E2 in Aqueous Humor of Patients with Cataract Surgery. / Matsuo, Toshihiko.

In: Journal of Ocular Pharmacology and Therapeutics, Vol. 20, No. 2, 04.2004, p. 101-106.

Research output: Contribution to journalArticle

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