PRL is best known for its role in enabling female mammals to produce milk. However, it is influential over a large number of functions; over 300 separate actions of PRL have been reported in various vertebrates. Control of water and salt balance is probably an important function especially in teleost fish. PRL universally acts in endocrine, autocrine, and paracrine manner through the PRL receptor that belongs to the type I cytokine receptor family. PRL has important cell turnover-related functions such as growth, differentiating and anti-apoptotic factors, especially in hematopoiesis, angiogenesis, and the immune system through several pathways.

Original languageEnglish
Title of host publicationHandbook of Hormones
Subtitle of host publicationComparative Endocrinology for Basic and Clinical Research
ISBN (Electronic)9780128010280
ISBN (Print)9780128010679
Publication statusPublished - Jan 1 2015


  • body fluid regulation
  • cytokine
  • dopamine
  • immune system
  • JAK/STAT pathway
  • lactation
  • Pit-1
  • pituitary
  • reproduction

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Prolactin'. Together they form a unique fingerprint.

Cite this