Prolactin

Tatsuya Sakamoto

doi:10.1016/B978-0-12-801028-0.00133-1

Prolactin

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

PRL is best known for its role in enabling female mammals to produce milk. However, it is influential over a large number of functions; over 300 separate actions of PRL have been reported in various vertebrates. Control of water and salt balance is probably an important function especially in teleost fish. PRL universally acts in endocrine, autocrine, and paracrine manner through the PRL receptor that belongs to the type I cytokine receptor family. PRL has important cell turnover-related functions such as growth, differentiating and anti-apoptotic factors, especially in hematopoiesis, angiogenesis, and the immune system through several pathways.

Original language	English
Title of host publication	Handbook of Hormones
Subtitle of host publication	Comparative Endocrinology for Basic and Clinical Research
Publisher	Elsevier
Pages	112,e15B-2-113,e15B-5
ISBN (Electronic)	9780128010280
ISBN (Print)	9780128010679
DOIs	https://doi.org/10.1016/B978-0-12-801028-0.00133-1
Publication status	Published - Jan 1 2015

Keywords

body fluid regulation
cytokine
dopamine
immune system
JAK/STAT pathway
lactation
Pit-1
pituitary
reproduction

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1016/B978-0-12-801028-0.00133-1

Cite this

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KW - reproduction

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ER -

Prolactin

Abstract

Keywords

ASJC Scopus subject areas

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