Projection of nucleus tractus solitarius units influenced by hepatoportal afferent signal to parabrachial nucleus

Motoi Kobashi, Akira Adachi

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

In urethan-chloralose anesthetized rats, units in the nucleus tractus solitarius (NTS) which antidromically responded to electrical stimulation of the parabrachial nucleus (PB) were investigated for their responses to hepatic-vagal afferent signals. Among 63 NTS units examined, 25 (40%) were excited, 17 (27%) inhibited and the remaining 21 (33%) unaffected by single shock electrical stimulation of the hepatic branch of the vagus nerve. Topical application of Na+ produced an increase in discharge rate of 9 units and a decrease in 5 units. Portal infusion of hypertonic saline produced an increase in discharge rate of 3 units and a decrease in 5 units. Furthermore, 3 units responded to both topical application of Na+ and portal infusion of hypertonic saline.

Original languageEnglish
Pages (from-to)153-158
Number of pages6
JournalJournal of the Autonomic Nervous System
Volume16
Issue number2
DOIs
Publication statusPublished - 1986

Fingerprint

Solitary Nucleus
Electric Stimulation
Chloralose
Vagus Nerve
Liver
Urethane
Shock
Parabrachial Nucleus

Keywords

  • antidromic activation
  • hepatic vagus
  • nucleus tractus solitarius (NTS)
  • osmoreception
  • parabrachial nucleus (PB)

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

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