TY - JOUR
T1 - Projection of nucleus tractus solitarius units influenced by hepatoportal afferent signal to parabrachial nucleus
AU - Kobashi, Motoi
AU - Adachi, Akira
N1 - Funding Information:
This work was partly supported by Grant 59570790 from the Ministry of Education, Science and Culture of Japan.
PY - 1986/6
Y1 - 1986/6
N2 - In urethan-chloralose anesthetized rats, units in the nucleus tractus solitarius (NTS) which antidromically responded to electrical stimulation of the parabrachial nucleus (PB) were investigated for their responses to hepatic-vagal afferent signals. Among 63 NTS units examined, 25 (40%) were excited, 17 (27%) inhibited and the remaining 21 (33%) unaffected by single shock electrical stimulation of the hepatic branch of the vagus nerve. Topical application of Na+ produced an increase in discharge rate of 9 units and a decrease in 5 units. Portal infusion of hypertonic saline produced an increase in discharge rate of 3 units and a decrease in 5 units. Furthermore, 3 units responded to both topical application of Na+ and portal infusion of hypertonic saline.
AB - In urethan-chloralose anesthetized rats, units in the nucleus tractus solitarius (NTS) which antidromically responded to electrical stimulation of the parabrachial nucleus (PB) were investigated for their responses to hepatic-vagal afferent signals. Among 63 NTS units examined, 25 (40%) were excited, 17 (27%) inhibited and the remaining 21 (33%) unaffected by single shock electrical stimulation of the hepatic branch of the vagus nerve. Topical application of Na+ produced an increase in discharge rate of 9 units and a decrease in 5 units. Portal infusion of hypertonic saline produced an increase in discharge rate of 3 units and a decrease in 5 units. Furthermore, 3 units responded to both topical application of Na+ and portal infusion of hypertonic saline.
KW - antidromic activation
KW - hepatic vagus
KW - nucleus tractus solitarius (NTS)
KW - osmoreception
KW - parabrachial nucleus (PB)
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U2 - 10.1016/0165-1838(86)90006-8
DO - 10.1016/0165-1838(86)90006-8
M3 - Article
C2 - 3722718
AN - SCOPUS:0022644585
VL - 16
SP - 153
EP - 158
JO - Journal of the Autonomic Nervous System
JF - Journal of the Autonomic Nervous System
SN - 1566-0702
IS - 2
ER -