TY - JOUR
T1 - Progressive paraplegia caused by recurrence of mantle-cell lymphoma with atypical spinal magnetic resonance imaging features
AU - Yamane, Hiromichi
AU - Ochi, Nobuaki
AU - Yamagishi, Tomoko
AU - Takigawa, Nagio
AU - Maeda, Yoshinobu
N1 - Publisher Copyright:
© 2015 Journal of Cancer Research and Therapeutics | Published by Wolters Kluwer - Medknow.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2015/10/1
Y1 - 2015/10/1
N2 - We describe a case of paraplegia, which had progressed rapidly in a 60-year-old Japanese man with mantle-cell lymphoma. (MCL). He admitted to our hospital due to lumbago and progressive muscle weakness of bilateral lower thighs lasting for 1. month, while he had the history of the systemic chemotherapy for MCL since 10 months. Magnetic resonance imaging. (MRI) revealed a wide-spreading intradural tumor situated in the spinal canal from L1 to L5 with an intervertebral slipped disk as the only site of recurrence. Laminectomy followed by salvage chemotherapy led disappearance of lumbago and paraplegia of the bilateral lower extremities. Although wide-spreading tumor formation in spinal canal without other involvement sites is very rare in MCL, physicians should be aware of such patterns of central nervous system. (CNS) relapse for the early diagnosis and adequate selection of treatment modality.
AB - We describe a case of paraplegia, which had progressed rapidly in a 60-year-old Japanese man with mantle-cell lymphoma. (MCL). He admitted to our hospital due to lumbago and progressive muscle weakness of bilateral lower thighs lasting for 1. month, while he had the history of the systemic chemotherapy for MCL since 10 months. Magnetic resonance imaging. (MRI) revealed a wide-spreading intradural tumor situated in the spinal canal from L1 to L5 with an intervertebral slipped disk as the only site of recurrence. Laminectomy followed by salvage chemotherapy led disappearance of lumbago and paraplegia of the bilateral lower extremities. Although wide-spreading tumor formation in spinal canal without other involvement sites is very rare in MCL, physicians should be aware of such patterns of central nervous system. (CNS) relapse for the early diagnosis and adequate selection of treatment modality.
KW - Intradural spinal involvement
KW - magnetic resonance imaging
KW - mantle-cell lymphoma
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U2 - 10.4103/0973-1482.154006
DO - 10.4103/0973-1482.154006
M3 - Article
C2 - 26881642
AN - SCOPUS:84959515008
VL - 11
SP - 1220
EP - 1222
JO - Journal of Cancer Research and Therapeutics
JF - Journal of Cancer Research and Therapeutics
SN - 0973-1482
IS - 4
ER -