Abstract
A 52-year-old man suffered from progressive multifocal leukoencephalopathy (PML) after human leukocyte antigen (HLA)-haploidentical transplantation with post-transplantation cyclophosphamide (PTCY). Mirtazapine, mefloquine, and cytarabine failed to improve his symptoms, and he finally died 4.5 months after PML onset. This is the first case report of a patient with PML after HLA-haploidentical transplantation with PTCY. Although T-cell replete HLA-haploidentical transplantation with PTCY has enabled early immune reconstitution, PML should be considered if a patient's mental condition deteriorates.
Original language | English |
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Article number | e12850 |
Journal | Transplant Infectious Disease |
Volume | 20 |
Issue number | 2 |
DOIs | |
Publication status | Published - Apr 2018 |
Keywords
- haploidentical transplantation
- post-transplantation cyclophosphamide
- progressive multifocal leukoencephalopathy
ASJC Scopus subject areas
- Infectious Diseases
- Transplantation