Prognostic factors in stage IB-IIB cervical adenocarcinoma patients treated with radical hysterectomy and pelvic lymphadenectomy

Junichi Kodama, Noriko Seki, Satoko Masahiro, Tomoyuki Kusumoto, Keiichiro Nakamura, Atsushi Hongo, Yuji Hiramatsu

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39 Citations (Scopus)

Abstract

Objectives: The purpose of the present study was to identify prognostic factors and patterns of recurrence in patients with stage IB-IIB cervical adenocarcinoma who had undergone radical surgery and to compare these patterns with those observed in squamous cell carcinoma (SCC) patients. Methods: We retrospectively reviewed 303 patients (97 with adenocarcinoma and 206 with SCC) with stage IB-IIB cervical cancer who had undergone radical hysterectomy and pelvic lymphadenectomy. Results: In the case of the adenocarcinoma patients, lymph node metastasis and parametrial invasion were independent indicators of disease-free survival, whereas lymph node metastasis was the only independent prognostic factor for the overall survival of the patients. The sites of recurrence did not significantly differ between the adenocarcinoma and SCC patients. In parametrium-positive patients, adenocarcinoma was found to be an independent prognostic factor for disease-free survival. In patients with positive pelvic lymph node, adenocarcinoma was found to be an independent prognostic factor for both disease-free and overall survival. Conclusions: Adenocarcinoma was found to be an independent prognostic factor for survival in patients with positive pelvic node or parametrial extension. Furthermore, the patterns of recurrence did not differ significantly between the adenocarcinoma and SCC patients.

Original languageEnglish
Pages (from-to)413-417
Number of pages5
JournalJournal of Surgical Oncology
Volume101
Issue number5
DOIs
Publication statusPublished - Apr 1 2010

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Lymph Node Excision
Hysterectomy
Adenocarcinoma
Squamous Cell Carcinoma
Disease-Free Survival
Lymph Nodes
Recurrence
Neoplasm Metastasis
Survival
Peritoneum
Uterine Cervical Neoplasms

Keywords

  • Adenocarcinoma
  • Prognosis
  • Squamous cell carcinoma

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Prognostic factors in stage IB-IIB cervical adenocarcinoma patients treated with radical hysterectomy and pelvic lymphadenectomy. / Kodama, Junichi; Seki, Noriko; Masahiro, Satoko; Kusumoto, Tomoyuki; Nakamura, Keiichiro; Hongo, Atsushi; Hiramatsu, Yuji.

In: Journal of Surgical Oncology, Vol. 101, No. 5, 01.04.2010, p. 413-417.

Research output: Contribution to journalArticle

Kodama, Junichi ; Seki, Noriko ; Masahiro, Satoko ; Kusumoto, Tomoyuki ; Nakamura, Keiichiro ; Hongo, Atsushi ; Hiramatsu, Yuji. / Prognostic factors in stage IB-IIB cervical adenocarcinoma patients treated with radical hysterectomy and pelvic lymphadenectomy. In: Journal of Surgical Oncology. 2010 ; Vol. 101, No. 5. pp. 413-417.
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