Prognostic factors in node-positive patients with stage IB-IIB cervical cancer treated by radical hysterectomy and pelvic lymphadenectomy

J. Kodama, N. Seki, Y. Ojima, K. Nakamura, A. Hongo, Y. Hiramatsu

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Objective: The purpose of the present study was to identify prognostic factors in surgically treated patients with stage IB-IIB cervical cancers, who also presented with positive pelvic nodes. Method: The patient population consisted of 68 individuals presenting with stage IB-IIB cervical cancers and with histologically proven pelvic lymph nodes. Result: We found no association between the type of adjuvant therapy and patient outcome. Multivariate analysis revealed that non-squamous histology was an independent prognostic factor for disease-free and overall survival rates. In squamous cell carcinomas, the bilateral nature of the positive nodes was found to be a significant factor for disease-free survival rates. In non-squamous cell carcinomas, positive nodes of more than 2 cm in size were found to be a significant factor for disease-free survival rates. Conclusion: Non-squamous histology was an independent prognostic factor and chemoradiotherapy did not improve the survival outcomes of the patients in this study population.

Original languageEnglish
Pages (from-to)130-135
Number of pages6
JournalInternational Journal of Gynecology and Obstetrics
Volume93
Issue number2
DOIs
Publication statusPublished - May 2006

Keywords

  • Cervical cancer
  • Chemoradiotherapy
  • Positive nodes
  • Prognosis

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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