A combination of 70 mg/m2. cis-platinum, 40 mg/m2. doxorubicin or 40 mg/m2 tetrahydropyranyldoxorubicin instead of doxorubicin, and angiotensin II was infused into the bilateral internal iliac artery for the treatment of 31 patients with advanced bladder cancer (T2~T4). Of the 31 patients, 9 achieved CR and 16 achieved PR. We researched the prognosis of the patients, and discuss the usefulness of intra-arterial infusion chemotherapy (Al). Of 5 who achieved CR and underwent no successive therapy, 4 had recurrence and 2 died from cancer. This means Al is not sufficient by itself. Of 9 who achieved CR or PR and who finally underwent total cystectomy, 6 are disease free now. Therefore, we may expect Al to be useful as an adjuvant therapy prior to total cystectomy. The problems with this study were the follow-up duration and the number of patients. After we have continued to follow up patients for over 5 years, have increased the number of patients, and have compared the results with those cases who received no Al, a final conclusion should be considered.
|Number of pages||5|
|Journal||Nishinihon Journal of Urology|
|Publication status||Published - Jan 1 1990|
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