Production of Antigenically Related Exocellular Elastolytic Proteases Mediating Hemagglutination by Vibrios

Munirul Alam, Shin ichi Miyoshi, Sumio Shinoda

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Exocellular proteases produced by Vibrio fluvialis, V. furnissii, V. metschnikovii and V. campbellii were characterized and compared to those of V. mimicus protease (VMP) and V. vulnificus protease (VVP). These proteases possessed both elastolytic and hemagglutinating abilities and were identified, except that of V. metschnikovii, as metalloprotease. Conversely, V. metschnikovii protease failed to exhibit some of the salient features for metalloproteases suggesting the existence of protease(s) other than metalloprotease. However, antibodies against VVP cross-reacted to these proteases and to VMP indicating antigenic relatedness amongst vibrio proteases. This study, thus, demonstrated the prevalent distributions of antigenically related proteases both in pathogenic and non-pathogenic vibrios, bringing their status as a virulence determinant into question.

Original languageEnglish
Pages (from-to)67-70
Number of pages4
JournalMICROBIOLOGY and IMMUNOLOGY
Volume39
Issue number1
DOIs
Publication statusPublished - Jan 1 1995

Keywords

  • Hemagglutinin
  • Protease
  • Vibrio

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Virology

Fingerprint Dive into the research topics of 'Production of Antigenically Related Exocellular Elastolytic Proteases Mediating Hemagglutination by Vibrios'. Together they form a unique fingerprint.

  • Cite this