Production of a novel percutaneous device realizing of prevention of germ infection made of a nono-scaled hydroxyapatite crystals/polymer composite

Yasumichi Kogai, Shoji Yasuda, Masahiro Okada, Junzo Tanaka, Tsutomu Furuzono

Research output: Contribution to conferencePaper

Abstract

Nano-scale hydroxyapatite(HAp) crystals were covalently bonded to the surface of the silk fibroin(SF) substrate through poly(MTPS) grafting on the substrate. A button-form percutaneous device was fabricated by transplanting the HAp/SF composite fibers onto the surface of a button made from a silicone compound via an adhesive. The device was white and had good flexibility. Cells were able to penetrate into the space among the composite fibers in three-dimensional tangle. Soft tissue is expected to behave in a manner similar to the penetration of the cells into the device. Animal experiments with a percutaneous implantation of the button-form device for short to long period will be reported in this conference.

Original languageEnglish
Number of pages1
Publication statusPublished - Oct 19 2006
Externally publishedYes
Event55th SPSJ Annual Meeting - Nagoya, Japan
Duration: May 24 2006May 26 2006

Other

Other55th SPSJ Annual Meeting
CountryJapan
CityNagoya
Period5/24/065/26/06

Keywords

  • Hydroxyapatite
  • Inorganic-organic composite
  • Silk fibroin

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Kogai, Y., Yasuda, S., Okada, M., Tanaka, J., & Furuzono, T. (2006). Production of a novel percutaneous device realizing of prevention of germ infection made of a nono-scaled hydroxyapatite crystals/polymer composite. Paper presented at 55th SPSJ Annual Meeting, Nagoya, Japan.