Abstract
TMSCl works as an acid catalyst precursor for selective esterification of L-aspartic and L-glutamic acids in the presence of primary, secondary and tertiary alcohols. Although excess TMSCl was required for the completion of esterification, the resulting alkyl TMS ether could be azeotropically removed by simple evaporation with alcohol.
| Original language | English |
|---|---|
| Pages (from-to) | 247-249 |
| Number of pages | 3 |
| Journal | Natural Product Communications |
| Volume | 12 |
| Issue number | 2 |
| Publication status | Published - 2017 |
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Keywords
- Acid catalyst
- Aspartic acid
- Esterification
- Protective group
- TMSCl
ASJC Scopus subject areas
- Medicine(all)
- Pharmacology
- Plant Science
- Drug Discovery
- Complementary and alternative medicine
Cite this
Product selectivity of esterification of L-aspartic acid and L-glutamic acid using chlorotrimethylsilane. / Takaishi, Tomohiro; Izumi, Minoru; Ota, Ryo; Inoue, Chieri; Kiyota, Hiromasa; Fukase, Koichi.
In: Natural Product Communications, Vol. 12, No. 2, 2017, p. 247-249.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Product selectivity of esterification of L-aspartic acid and L-glutamic acid using chlorotrimethylsilane
AU - Takaishi, Tomohiro
AU - Izumi, Minoru
AU - Ota, Ryo
AU - Inoue, Chieri
AU - Kiyota, Hiromasa
AU - Fukase, Koichi
PY - 2017
Y1 - 2017
N2 - TMSCl works as an acid catalyst precursor for selective esterification of L-aspartic and L-glutamic acids in the presence of primary, secondary and tertiary alcohols. Although excess TMSCl was required for the completion of esterification, the resulting alkyl TMS ether could be azeotropically removed by simple evaporation with alcohol.
AB - TMSCl works as an acid catalyst precursor for selective esterification of L-aspartic and L-glutamic acids in the presence of primary, secondary and tertiary alcohols. Although excess TMSCl was required for the completion of esterification, the resulting alkyl TMS ether could be azeotropically removed by simple evaporation with alcohol.
KW - Acid catalyst
KW - Aspartic acid
KW - Esterification
KW - Protective group
KW - TMSCl
UR - http://www.scopus.com/inward/record.url?scp=85019118145&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85019118145&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85019118145
VL - 12
SP - 247
EP - 249
JO - Natural Product Communications
JF - Natural Product Communications
SN - 1934-578X
IS - 2
ER -