Primary neurons maintain their central axonal arbors in the spinal dorsal horn following peripheral nerve injury: an anatomical analysis using transganglionic transport of horseradish peroxidase

Tomosada Sugimoto, Stephen Gobel

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

This study in adult cats demonstrates that primary neurons of all sizes survive following the transection and capping with a polyethylene tube of their peripheral processes in the superficial radial nerve. The central axonal arbors of these injured primary neurons remain intact and maintain their normal topographic position across laminae I-VI of the cervical (C6-C8) dorsal horn. In addition, they maintain their synaptic vesicles, some of their synaptic connections and their ability to transport horseradish peroxidase transganglionically.

Original languageEnglish
Pages (from-to)377-381
Number of pages5
JournalBrain Research
Volume248
Issue number2
DOIs
Publication statusPublished - Sep 30 1982
Externally publishedYes

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Keywords

  • peripheral nerve injury
  • primary neurons
  • spinal dorsal horn
  • transganglionic transport

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

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