Abstract
The purpose of this study was to demonstrate immunohistochemically the localization and distibution of human β-defensin-2 (HBD-2), a peptide with antimicrobial activity, in oral carcinoma tissues. Tissue samples were embedded in paraffin, and HBD-2 was immunostained by the streptavidin-biotin coupled peroxidase method. Cancer cells in the cornified region of well differentiated squamous cell carcinomas were stained intensely. Stained cancer cells detected by anti-HBD-2 antibody were scattered among the cells of the non-cornified region.
Original language | English |
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Pages (from-to) | 2005-2007 |
Number of pages | 3 |
Journal | Anticancer research |
Volume | 20 |
Issue number | 3 B |
Publication status | Published - 2000 |
Keywords
- Defensin
- HBD-2
- Oral carcinoma
- Squamous cell carcinoma
ASJC Scopus subject areas
- Oncology
- Cancer Research