Preparation of transparent hydroxyapatite/citric acid particle films

Zizhen Liu, Takuya Kataoka, Daisuke Kawagoe, Daichi Noda, Yadong Chai, Motohiro Tagaya

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Transparent hydroxyapatite/citric acid (Cit/HA) particulate film formation and the stability in biological solution were investigated. Negatively charged Cit/HA nanoparticles were synthesized, and the particulate films were prepared by a spin-coat method through water or ethanol dispersion. As a result, the crack-free and transparent Cit/HA films were prepared from water dispersion, which exhibited the better optical properties as compared with the films prepared from ethanol dispersion. The Cit/HA films exhibited higher optical transmittance with increasing the hybridized Cit amount, and the highest transmittance in the visible light region exceeded 80%. Moreover, the calcined film had long-term stability in phosphate-buffered saline while maintaining high transparency, which is expected to be used as a candidate coating film for cell culture substrates.

Original languageEnglish
Article number100316
JournalColloids and Interface Science Communications
Publication statusPublished - Nov 2020
Externally publishedYes


  • Hydroxyapatite nanoparticles
  • Inorganic/organic hybrids
  • Nanobiomaterials
  • Transparent bioceramics

ASJC Scopus subject areas

  • Biotechnology
  • Physical and Theoretical Chemistry
  • Surfaces, Coatings and Films
  • Colloid and Surface Chemistry
  • Materials Chemistry


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