Preparation of quinoline hexose analogs as novel chloroquine-resistant malaria treatments (1). Synthesis of 4-hydroxyquinoline-β-glucosides

Hiroshi Suzuki, Nagwa S.M. Aly, Yusuke Wataya, Hye Sook Kim, Ikumi Tamai, Masaki Kita, Daisuke Uemura

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Abstract

Quinoline hexose analogs are expected to be useful as novel agents for treatment of chloroquine-resistant malaria. Here, we report preparation of 4-hydroxy quinoline-β-glucosides from anilines in 4 steps.

Original languageEnglish
Pages (from-to)821-824
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume55
Issue number5
DOIs
Publication statusPublished - May 1 2007

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Keywords

  • Chloroquine-resistant malaria treatment
  • Malaria
  • Quinoline-glucosides

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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