Preparation of porous chitosan-siloxane hybrids coated with hydroxyapatite particles

Yuki Shirosaki, Kohei Okamoto, Satoshi Hayakawa, Akiyoshi Osaka, Takuji Asano

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

This paper describes the apatite deposition of chitosan-silicate porous hybrids derived from chitosan and γ-glycidoxypropyltrimethoxysilane (GPTMS) in alkaline phosphate solution. The preparation of porous hybrids with needle-like apatite on their surfaces is described. Following apatite deposition the porous hybrids maintained high porosity. The enzymatic degradation rate was low even after 6 months and the porous hybrids were very flexible and cut easily using surgical scissors.

Original languageEnglish
Article number392940
JournalBioMed research international
Volume2015
DOIs
Publication statusPublished - 2015

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

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