Preparation of novel structures by ultra high pressure treatment for aqueous PEG/polysaccharides two-phase system

Yoshivuki Miura, Kimio Kurita, Tsuyoshi Kimura, Kwangwoo Nam, Shingo Mutsuo, Hidekazu Yoshizawa, Masahiro Okada, Tsutomu Furuzono, Toshiya Fujisao, Akio Kishida

Research output: Contribution to conferencePaper

Abstract

In this study, the preparation of novel structures by ultra high pressure (UHP) treatment for aqueous PEG/polysaccharides two-phase system was investigated. For polyethylene glycol (PEG) or dextran (DEX) solutions, the clear solutions were maintained after UHP treatment. On the other hand, when PEG (Mw: 6,000 or 8,000) were mixed with DEX (Mw:60,000-90,000) or pullulan, the solution with light scattering was obtained. After UHP treatment, aqueous two-phase separation having light scattering in lower phase was obtained for all cases, suggesting that apparent molecular weight was increased by the formation of PEG/ polysaccharides complex. DLS measurement of them before/after UHP treatment was carried out. The particle size was increased by UHP treatment, then decreased by heat treatment at 50 degrees, indicating the formation of novel hydrogen bonding structures.

Original languageEnglish
Number of pages1
Publication statusPublished - Oct 18 2006
Externally publishedYes
Event55th SPSJ Annual Meeting - Nagoya, Japan
Duration: May 24 2006May 26 2006

Other

Other55th SPSJ Annual Meeting
CountryJapan
CityNagoya
Period5/24/065/26/06

Keywords

  • Aqueous two-phase system
  • Ultra high pressure treatment

ASJC Scopus subject areas

  • Engineering(all)

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    Miura, Y., Kurita, K., Kimura, T., Nam, K., Mutsuo, S., Yoshizawa, H., Okada, M., Furuzono, T., Fujisao, T., & Kishida, A. (2006). Preparation of novel structures by ultra high pressure treatment for aqueous PEG/polysaccharides two-phase system. Paper presented at 55th SPSJ Annual Meeting, Nagoya, Japan.