Preparation of novel specific aminopeptidase inhibitors with a cyclic imide skeleton

Medicine & Life Sciences

• N-(2,6-diethylphenyl)homophthalimide 100%
• Imides 66%
• Aminopeptidases 52%
• enkephalin degrading enzyme 51%
• ubenimex 29%
• Phenylhomophthalimide 25%
• N-phenylphthalimide 22%
• 4-methyl-coumaryl-7-amide 18%
• actinonin 17%
• phthalimide 17%
• Peptide Hydrolases 16%
• 1,2,3,4-tetrahydroisoquinoline 15%
• CD13 Antigens 13%
• Puromycin 13%
• Protein Sequence Analysis 11%
• Structure-Activity Relationship 11%
• Precursor Cell Lymphoblastic Leukemia-Lymphoma 9%
• Electrons 7%
• Peptides 6%
• Enzymes 5%
• Neoplasms 3%

Chemical Compounds

• Bestatin 60%
• Imide 37%
• Actinonin 35%
• 1,2,3,4-tetrahydroisoquinoline 28%
• Puromycin 26%
• Phthalimide 24%
• Tautomerization 20%
• Structure-Activity Relationship 16%
• Peptide 11%
• Electron Particle 10%
• Acid 6%