Preparation of Nanocapsules with Alginate/Polylysine Complex Wall

Masahiko Abe, Kensuke Tanaka, Ai Nakayama, Tamotsu Kondo, Koji Tsuchiya, Veerapat Tantayakom, Takahiro Ohkubo, Hideki Sakai

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2 Citations (Scopus)

Abstract

This paper deals with a novel preparation method of nanocapsules with alginate/polylysine complex wall. The preparation method consisted of the following steps: dispersion of an aqueous sodium alginate solution into cyclohexane to give a W/O emulsion, preparation of calcium alginate gel beads by adding the emulsion into a calcium aerosol OT solution in cyclohexane, and alginate/polylysine complex wall formation on the surface of calcium alginate beads by adding the beads into an aqueous poly-L-lysine solution. The size of alginate/polylysine complex capsules thus prepared was found to be 100-500 nm. Moreover, an attempt was made to prepare much smaller capsules using a laboratory-made apparatus for electrocapillary emulsification and the capsule size could be reduced to about 40 nm.

Original languageEnglish
Pages (from-to)615-621
Number of pages7
JournalJournal of Oleo Science
Volume55
Issue number12
DOIs
Publication statusPublished - 2006
Externally publishedYes

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Keywords

  • alginate
  • electrocapillary emulsification
  • nanocapsule
  • polylysine

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Abe, M., Tanaka, K., Nakayama, A., Kondo, T., Tsuchiya, K., Tantayakom, V., Ohkubo, T., & Sakai, H. (2006). Preparation of Nanocapsules with Alginate/Polylysine Complex Wall. Journal of Oleo Science, 55(12), 615-621. https://doi.org/10.5650/jos.55.615