Abstract
We have previously developed biodegradable β-tricalcium phosphate (β-TCP) cement based on the chelate-setting mechanism of inositol phosphate (IP6). The β-TCP cement powder for the cement fabrication was prepared via a novel powder preparation process, in which the starting β-TCP powders were prepared by simultaneous ball-milling and surface-modification in the IP6 solution. In the present study, the novel powder preparation process was applied to an α-TCP powder, and effect of milling time and beads size for ball-milling on the material properties of the a-TCP powders was investigated. The α-TCP powder ball-milled in 1000 ppm IP6 solution for 4 h with 2 mm-diameter beads was composed of single phase α-TCP with the smallest particle size of 2.2 um. Dissolution of 4 h-milled α-TCP powder was approximately twice higher than that of starting α-TCP powder before ball-milling. The α-TCP powder with high dissolution property prepared via the novel powder preparation process is potential candidate for fabrication of the chelate-setting cement.
| Original language | English |
|---|---|
| Title of host publication | Bioceramics 26 |
| Publisher | Trans Tech Publications Ltd |
| Pages | 113-118 |
| Number of pages | 6 |
| Volume | 631 |
| ISBN (Print) | 9783038352822 |
| DOIs | |
| Publication status | Published - 2015 |
| Event | 26th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2014 - Barcelona, Spain Duration: Nov 6 2014 → Nov 8 2014 |
Publication series
| Name | Key Engineering Materials |
|---|---|
| Volume | 631 |
| ISSN (Print) | 10139826 |
Other
| Other | 26th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2014 |
|---|---|
| Country | Spain |
| City | Barcelona |
| Period | 11/6/14 → 11/8/14 |
Fingerprint
Keywords
- Calcium-phosphate cement
- Inositol phosphate
- Surface modification
- α-Tricalcium phosphate
ASJC Scopus subject areas
- Materials Science(all)
- Mechanics of Materials
- Mechanical Engineering
Cite this
Preparation of α-Tricalcium Phosphate Powders Surface-modified with Inositol Phosphate for Cement Fabrication. / Konishi, Toshiisa; Honda, Michiyo; Yoshioka, Tomohiko; Hayakawa, Satoshi; Aizawa, Mamoru.
Bioceramics 26. Vol. 631 Trans Tech Publications Ltd, 2015. p. 113-118 (Key Engineering Materials; Vol. 631).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Preparation of α-Tricalcium Phosphate Powders Surface-modified with Inositol Phosphate for Cement Fabrication
AU - Konishi, Toshiisa
AU - Honda, Michiyo
AU - Yoshioka, Tomohiko
AU - Hayakawa, Satoshi
AU - Aizawa, Mamoru
PY - 2015
Y1 - 2015
N2 - We have previously developed biodegradable β-tricalcium phosphate (β-TCP) cement based on the chelate-setting mechanism of inositol phosphate (IP6). The β-TCP cement powder for the cement fabrication was prepared via a novel powder preparation process, in which the starting β-TCP powders were prepared by simultaneous ball-milling and surface-modification in the IP6 solution. In the present study, the novel powder preparation process was applied to an α-TCP powder, and effect of milling time and beads size for ball-milling on the material properties of the a-TCP powders was investigated. The α-TCP powder ball-milled in 1000 ppm IP6 solution for 4 h with 2 mm-diameter beads was composed of single phase α-TCP with the smallest particle size of 2.2 um. Dissolution of 4 h-milled α-TCP powder was approximately twice higher than that of starting α-TCP powder before ball-milling. The α-TCP powder with high dissolution property prepared via the novel powder preparation process is potential candidate for fabrication of the chelate-setting cement.
AB - We have previously developed biodegradable β-tricalcium phosphate (β-TCP) cement based on the chelate-setting mechanism of inositol phosphate (IP6). The β-TCP cement powder for the cement fabrication was prepared via a novel powder preparation process, in which the starting β-TCP powders were prepared by simultaneous ball-milling and surface-modification in the IP6 solution. In the present study, the novel powder preparation process was applied to an α-TCP powder, and effect of milling time and beads size for ball-milling on the material properties of the a-TCP powders was investigated. The α-TCP powder ball-milled in 1000 ppm IP6 solution for 4 h with 2 mm-diameter beads was composed of single phase α-TCP with the smallest particle size of 2.2 um. Dissolution of 4 h-milled α-TCP powder was approximately twice higher than that of starting α-TCP powder before ball-milling. The α-TCP powder with high dissolution property prepared via the novel powder preparation process is potential candidate for fabrication of the chelate-setting cement.
KW - Calcium-phosphate cement
KW - Inositol phosphate
KW - Surface modification
KW - α-Tricalcium phosphate
UR - http://www.scopus.com/inward/record.url?scp=84921751136&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84921751136&partnerID=8YFLogxK
U2 - 10.4028/www.scientific.net.KEM.631.113
DO - 10.4028/www.scientific.net.KEM.631.113
M3 - Conference contribution
AN - SCOPUS:84921751136
SN - 9783038352822
VL - 631
T3 - Key Engineering Materials
SP - 113
EP - 118
BT - Bioceramics 26
PB - Trans Tech Publications Ltd
ER -