Preparation, characterization and biological assessment of bioactive and mesoporous silica nanoparticle coatings for bone regeneration

Song Chen, Kanji Tsuru, Satoshi Hayakawa, Akiyoshi Osaka

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Bioactive porous silica particle coatings were fabricated on the stainless steel substrates as bone repairing implants to enhance the apatite deposition. The particles were prepared from tetraethoxysilane (TEOS) and cetyltrimethylammonium bromide (CTAB) via the sol-gel method and then calcined at 600°C for 2 h to produce the porous structure. Subsequently, the clean substrates were sequentially soaked in the chitosan, silica and calcium alginate solutions to obtain the chitosan/silica/calcium alginate coatings via the charged layer-by-layer deposition technique. The treated substrates deposited bioactive apatite when soaked in the Kokubo's simulated body fluid (SBF) and exhibited bioactivity. Thus, such bioactive porous silica coatings are applicable to the reservoirs for storing and releasing the bone factors.

Original languageEnglish
Title of host publicationA Global Road Map for Ceramic Materials and Technologies: Forecasting the Future of Ceramics, International Ceramic Federation - 2nd International Congress on Ceramics, ICC 2008, Final Programme
Publication statusPublished - 2008
Event2nd International Congress on Ceramics, ICC 2008 - Verona, Italy
Duration: Jun 29 2008Jul 4 2008

Other

Other2nd International Congress on Ceramics, ICC 2008
CountryItaly
CityVerona
Period6/29/087/4/08

Fingerprint

Silicon Dioxide
Bone
Silica
Nanoparticles
Apatites
Coatings
Alginate
Apatite
Chitosan
Calcium
Substrates
Body fluids
Stainless Steel
Bioactivity
Sol-gel process
Stainless steel
Polymers
alginic acid

ASJC Scopus subject areas

  • Ceramics and Composites

Cite this

Chen, S., Tsuru, K., Hayakawa, S., & Osaka, A. (2008). Preparation, characterization and biological assessment of bioactive and mesoporous silica nanoparticle coatings for bone regeneration. In A Global Road Map for Ceramic Materials and Technologies: Forecasting the Future of Ceramics, International Ceramic Federation - 2nd International Congress on Ceramics, ICC 2008, Final Programme

Preparation, characterization and biological assessment of bioactive and mesoporous silica nanoparticle coatings for bone regeneration. / Chen, Song; Tsuru, Kanji; Hayakawa, Satoshi; Osaka, Akiyoshi.

A Global Road Map for Ceramic Materials and Technologies: Forecasting the Future of Ceramics, International Ceramic Federation - 2nd International Congress on Ceramics, ICC 2008, Final Programme. 2008.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Chen, S, Tsuru, K, Hayakawa, S & Osaka, A 2008, Preparation, characterization and biological assessment of bioactive and mesoporous silica nanoparticle coatings for bone regeneration. in A Global Road Map for Ceramic Materials and Technologies: Forecasting the Future of Ceramics, International Ceramic Federation - 2nd International Congress on Ceramics, ICC 2008, Final Programme. 2nd International Congress on Ceramics, ICC 2008, Verona, Italy, 6/29/08.
Chen S, Tsuru K, Hayakawa S, Osaka A. Preparation, characterization and biological assessment of bioactive and mesoporous silica nanoparticle coatings for bone regeneration. In A Global Road Map for Ceramic Materials and Technologies: Forecasting the Future of Ceramics, International Ceramic Federation - 2nd International Congress on Ceramics, ICC 2008, Final Programme. 2008
Chen, Song ; Tsuru, Kanji ; Hayakawa, Satoshi ; Osaka, Akiyoshi. / Preparation, characterization and biological assessment of bioactive and mesoporous silica nanoparticle coatings for bone regeneration. A Global Road Map for Ceramic Materials and Technologies: Forecasting the Future of Ceramics, International Ceramic Federation - 2nd International Congress on Ceramics, ICC 2008, Final Programme. 2008.
@inproceedings{8bde9f62ddbf4678892dd230192528c3,
title = "Preparation, characterization and biological assessment of bioactive and mesoporous silica nanoparticle coatings for bone regeneration",
abstract = "Bioactive porous silica particle coatings were fabricated on the stainless steel substrates as bone repairing implants to enhance the apatite deposition. The particles were prepared from tetraethoxysilane (TEOS) and cetyltrimethylammonium bromide (CTAB) via the sol-gel method and then calcined at 600°C for 2 h to produce the porous structure. Subsequently, the clean substrates were sequentially soaked in the chitosan, silica and calcium alginate solutions to obtain the chitosan/silica/calcium alginate coatings via the charged layer-by-layer deposition technique. The treated substrates deposited bioactive apatite when soaked in the Kokubo's simulated body fluid (SBF) and exhibited bioactivity. Thus, such bioactive porous silica coatings are applicable to the reservoirs for storing and releasing the bone factors.",
author = "Song Chen and Kanji Tsuru and Satoshi Hayakawa and Akiyoshi Osaka",
year = "2008",
language = "English",
isbn = "9788880800842",
booktitle = "A Global Road Map for Ceramic Materials and Technologies: Forecasting the Future of Ceramics, International Ceramic Federation - 2nd International Congress on Ceramics, ICC 2008, Final Programme",

}

TY - GEN

T1 - Preparation, characterization and biological assessment of bioactive and mesoporous silica nanoparticle coatings for bone regeneration

AU - Chen, Song

AU - Tsuru, Kanji

AU - Hayakawa, Satoshi

AU - Osaka, Akiyoshi

PY - 2008

Y1 - 2008

N2 - Bioactive porous silica particle coatings were fabricated on the stainless steel substrates as bone repairing implants to enhance the apatite deposition. The particles were prepared from tetraethoxysilane (TEOS) and cetyltrimethylammonium bromide (CTAB) via the sol-gel method and then calcined at 600°C for 2 h to produce the porous structure. Subsequently, the clean substrates were sequentially soaked in the chitosan, silica and calcium alginate solutions to obtain the chitosan/silica/calcium alginate coatings via the charged layer-by-layer deposition technique. The treated substrates deposited bioactive apatite when soaked in the Kokubo's simulated body fluid (SBF) and exhibited bioactivity. Thus, such bioactive porous silica coatings are applicable to the reservoirs for storing and releasing the bone factors.

AB - Bioactive porous silica particle coatings were fabricated on the stainless steel substrates as bone repairing implants to enhance the apatite deposition. The particles were prepared from tetraethoxysilane (TEOS) and cetyltrimethylammonium bromide (CTAB) via the sol-gel method and then calcined at 600°C for 2 h to produce the porous structure. Subsequently, the clean substrates were sequentially soaked in the chitosan, silica and calcium alginate solutions to obtain the chitosan/silica/calcium alginate coatings via the charged layer-by-layer deposition technique. The treated substrates deposited bioactive apatite when soaked in the Kokubo's simulated body fluid (SBF) and exhibited bioactivity. Thus, such bioactive porous silica coatings are applicable to the reservoirs for storing and releasing the bone factors.

UR - http://www.scopus.com/inward/record.url?scp=84872161434&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84872161434&partnerID=8YFLogxK

M3 - Conference contribution

SN - 9788880800842

BT - A Global Road Map for Ceramic Materials and Technologies: Forecasting the Future of Ceramics, International Ceramic Federation - 2nd International Congress on Ceramics, ICC 2008, Final Programme

ER -