Abstract
To determine the effectiveness of living-donor lobar lung transplantation (LDLLT), it is necessary to predict the recipient's postoperative lung function. Traditionally, Date's formula, also called the seg-mental ratio, has used the number of lung segments to estimate the forced vital capacity (FVC) of grafts in LDLLT. To provide a more precise estimate of graft FVC, we calculated the volumes of the lower lobe and total lung using three-dimensional computed tomography (3D-CT) and the volume ratio between them. We calculated the volume ratio in 52 donors and tested the difference between the seg-mental volume ratios with a one-tailed f-test. We also calculated the predicted graft FVC in 21 LDLLTs using the segmental ratio pFVC(c) and the volume ratio pFVC(v), and then found the Pearson's correlation coefficients for both pFVC(c) and pFVC(v) with the recipients' actual FVC (rFVC) measured spirometrically 6 months after surgery. Significant differences were found between the segmental ratio and the average volume ratio for both sides (right, p - 0.03; left, p - 0.0003). Both pFVC(c) and pFVC(v) correlated significantly with rFVC at 6 months after surgery (p = 0.007 and 0.006). Both the conventional and the volumetric methods provided FVC predictions that correlated significantly with measured postoperative FVC.
| Original language | English |
|---|---|
| Pages (from-to) | 265-269 |
| Number of pages | 5 |
| Journal | Acta Medica Okayama |
| Volume | 65 |
| Issue number | 4 |
| Publication status | Published - Aug 2011 |
Fingerprint
Keywords
- 3D-CT volumetry
- Living-donor lobar lung transplantation
ASJC Scopus subject areas
- Medicine(all)
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Preoperative graft volume assessment with 3D-CT volumetry in living-donor lobar lung transplantations. / Kojima, Katsuhide; Kato, Katsuya; Oto, Takahiro; Mitsuhashi, Toshiharu; Shinya, Takayoshi; Sei, Tetsuro; Okumura, Yoshihiro; Sato, Shuhei; Miyoshi, Shinichiro; Kanazawa, Susumu.
In: Acta Medica Okayama, Vol. 65, No. 4, 08.2011, p. 265-269.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Preoperative graft volume assessment with 3D-CT volumetry in living-donor lobar lung transplantations
AU - Kojima, Katsuhide
AU - Kato, Katsuya
AU - Oto, Takahiro
AU - Mitsuhashi, Toshiharu
AU - Shinya, Takayoshi
AU - Sei, Tetsuro
AU - Okumura, Yoshihiro
AU - Sato, Shuhei
AU - Miyoshi, Shinichiro
AU - Kanazawa, Susumu
PY - 2011/8
Y1 - 2011/8
N2 - To determine the effectiveness of living-donor lobar lung transplantation (LDLLT), it is necessary to predict the recipient's postoperative lung function. Traditionally, Date's formula, also called the seg-mental ratio, has used the number of lung segments to estimate the forced vital capacity (FVC) of grafts in LDLLT. To provide a more precise estimate of graft FVC, we calculated the volumes of the lower lobe and total lung using three-dimensional computed tomography (3D-CT) and the volume ratio between them. We calculated the volume ratio in 52 donors and tested the difference between the seg-mental volume ratios with a one-tailed f-test. We also calculated the predicted graft FVC in 21 LDLLTs using the segmental ratio pFVC(c) and the volume ratio pFVC(v), and then found the Pearson's correlation coefficients for both pFVC(c) and pFVC(v) with the recipients' actual FVC (rFVC) measured spirometrically 6 months after surgery. Significant differences were found between the segmental ratio and the average volume ratio for both sides (right, p - 0.03; left, p - 0.0003). Both pFVC(c) and pFVC(v) correlated significantly with rFVC at 6 months after surgery (p = 0.007 and 0.006). Both the conventional and the volumetric methods provided FVC predictions that correlated significantly with measured postoperative FVC.
AB - To determine the effectiveness of living-donor lobar lung transplantation (LDLLT), it is necessary to predict the recipient's postoperative lung function. Traditionally, Date's formula, also called the seg-mental ratio, has used the number of lung segments to estimate the forced vital capacity (FVC) of grafts in LDLLT. To provide a more precise estimate of graft FVC, we calculated the volumes of the lower lobe and total lung using three-dimensional computed tomography (3D-CT) and the volume ratio between them. We calculated the volume ratio in 52 donors and tested the difference between the seg-mental volume ratios with a one-tailed f-test. We also calculated the predicted graft FVC in 21 LDLLTs using the segmental ratio pFVC(c) and the volume ratio pFVC(v), and then found the Pearson's correlation coefficients for both pFVC(c) and pFVC(v) with the recipients' actual FVC (rFVC) measured spirometrically 6 months after surgery. Significant differences were found between the segmental ratio and the average volume ratio for both sides (right, p - 0.03; left, p - 0.0003). Both pFVC(c) and pFVC(v) correlated significantly with rFVC at 6 months after surgery (p = 0.007 and 0.006). Both the conventional and the volumetric methods provided FVC predictions that correlated significantly with measured postoperative FVC.
KW - 3D-CT volumetry
KW - Living-donor lobar lung transplantation
UR - http://www.scopus.com/inward/record.url?scp=80052685842&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80052685842&partnerID=8YFLogxK
M3 - Article
C2 - 21860533
AN - SCOPUS:80052685842
VL - 65
SP - 265
EP - 269
JO - Acta Medica Okayama
JF - Acta Medica Okayama
SN - 0386-300X
IS - 4
ER -