Abstract
Introduction Recent studies suggest positive associations between prenatal exposure to ambient air pollution and neurodevelopment of children, but evidence on the adverse effects of exposure to air pollution on child neurobehavioral development remains limited. We thus examined associations between prenatal exposure to outdoor air pollution and child behavioral problems at school age, using data from a nationwide population-based longitudinal survey in Japan, where participants were recruited in 2001 and are continuously followed. Methods Suspended particulate matter (SPM), nitrogen dioxide, and sulfur dioxide concentrations during the 9 months before birth were obtained at municipality level and assigned to those participants born in the corresponding municipality. We analyzed data from singleton births with linked pollution data available (e.g., n = 33,911 for SPM). We used responses to survey questions about behavioral problems at age 8 years. We conducted multilevel logistic regression analysis, adjusting for individual and municipality-level variables. Results Air pollution exposure during gestation was positively associated with risk for behavioral problems related to attention and delinquent or aggressive behavior. In the fully adjusted models, odds ratios following a one-interquartile-range increase in SPM were 1.06 (95% confidence interval: 1.01, 1.11) for interrupting others, 1.09 (1.03, 1.15) for failure to pay attention when crossing a street, 1.06 (1.01, 1.11) for lying, and 1.07 (1.02, 1.13) for causing public disturbance. Conclusions Prenatal exposure to outdoor air pollution was associated with behavioral problems related to attention and delinquent or aggressive behavior at age 8 years in a nationally representative sample in Japan.
| Original language | English |
|---|---|
| Pages (from-to) | 192-198 |
| Number of pages | 7 |
| Journal | Environment International |
| Volume | 99 |
| DOIs | |
| Publication status | Published - 2017 |
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Keywords
- Air pollution
- Behavior
- Epidemiology
- Nitrogen dioxide
- Particulate matter
- Sulfur dioxide
ASJC Scopus subject areas
- Environmental Science(all)
Cite this
Prenatal exposure to outdoor air pollution and child behavioral problems at school age in Japan. / Yorifuji, Takashi; Kashima, Saori; Diez, Midory Higa; Kado, Yoko; Sanada, Satoshi; Doi, Hiroyuki.
In: Environment International, Vol. 99, 2017, p. 192-198.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prenatal exposure to outdoor air pollution and child behavioral problems at school age in Japan
AU - Yorifuji, Takashi
AU - Kashima, Saori
AU - Diez, Midory Higa
AU - Kado, Yoko
AU - Sanada, Satoshi
AU - Doi, Hiroyuki
PY - 2017
Y1 - 2017
N2 - Introduction Recent studies suggest positive associations between prenatal exposure to ambient air pollution and neurodevelopment of children, but evidence on the adverse effects of exposure to air pollution on child neurobehavioral development remains limited. We thus examined associations between prenatal exposure to outdoor air pollution and child behavioral problems at school age, using data from a nationwide population-based longitudinal survey in Japan, where participants were recruited in 2001 and are continuously followed. Methods Suspended particulate matter (SPM), nitrogen dioxide, and sulfur dioxide concentrations during the 9 months before birth were obtained at municipality level and assigned to those participants born in the corresponding municipality. We analyzed data from singleton births with linked pollution data available (e.g., n = 33,911 for SPM). We used responses to survey questions about behavioral problems at age 8 years. We conducted multilevel logistic regression analysis, adjusting for individual and municipality-level variables. Results Air pollution exposure during gestation was positively associated with risk for behavioral problems related to attention and delinquent or aggressive behavior. In the fully adjusted models, odds ratios following a one-interquartile-range increase in SPM were 1.06 (95% confidence interval: 1.01, 1.11) for interrupting others, 1.09 (1.03, 1.15) for failure to pay attention when crossing a street, 1.06 (1.01, 1.11) for lying, and 1.07 (1.02, 1.13) for causing public disturbance. Conclusions Prenatal exposure to outdoor air pollution was associated with behavioral problems related to attention and delinquent or aggressive behavior at age 8 years in a nationally representative sample in Japan.
AB - Introduction Recent studies suggest positive associations between prenatal exposure to ambient air pollution and neurodevelopment of children, but evidence on the adverse effects of exposure to air pollution on child neurobehavioral development remains limited. We thus examined associations between prenatal exposure to outdoor air pollution and child behavioral problems at school age, using data from a nationwide population-based longitudinal survey in Japan, where participants were recruited in 2001 and are continuously followed. Methods Suspended particulate matter (SPM), nitrogen dioxide, and sulfur dioxide concentrations during the 9 months before birth were obtained at municipality level and assigned to those participants born in the corresponding municipality. We analyzed data from singleton births with linked pollution data available (e.g., n = 33,911 for SPM). We used responses to survey questions about behavioral problems at age 8 years. We conducted multilevel logistic regression analysis, adjusting for individual and municipality-level variables. Results Air pollution exposure during gestation was positively associated with risk for behavioral problems related to attention and delinquent or aggressive behavior. In the fully adjusted models, odds ratios following a one-interquartile-range increase in SPM were 1.06 (95% confidence interval: 1.01, 1.11) for interrupting others, 1.09 (1.03, 1.15) for failure to pay attention when crossing a street, 1.06 (1.01, 1.11) for lying, and 1.07 (1.02, 1.13) for causing public disturbance. Conclusions Prenatal exposure to outdoor air pollution was associated with behavioral problems related to attention and delinquent or aggressive behavior at age 8 years in a nationally representative sample in Japan.
KW - Air pollution
KW - Behavior
KW - Epidemiology
KW - Nitrogen dioxide
KW - Particulate matter
KW - Sulfur dioxide
UR - http://www.scopus.com/inward/record.url?scp=85028242884&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85028242884&partnerID=8YFLogxK
U2 - 10.1016/j.envint.2016.11.016
DO - 10.1016/j.envint.2016.11.016
M3 - Article
C2 - 27890345
AN - SCOPUS:85028242884
VL - 99
SP - 192
EP - 198
JO - Environmental International
JF - Environmental International
SN - 0160-4120
ER -