Prenatal diagnosis of QT prolongation by fetal magnetocardiogram - Use of QRS and T-wave current-arrow maps

Akihiko Kandori, Tsuyoshi Miyashita, Keiji Tsukada, Takayoshi Hosono, Susumu Miyashita, Yoshihide Chiba, Hitoshi Horigome, Sadahiko Shigemitsu, Mitsuhiro Asaka

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

To determine the T wave of a fetal magnetocardiogram (FMCG), we have evaluated the T/QRS ratio and obtained current-arrow maps that indicate weak currents. We measured FMCG signals for 52 normal fetuses and two abnormal fetuses with prolonged QT waves by using three superconducting quantum interference device (SQUID) systems: a nine-channel system, a 12-channel vector system and a 64-channel system. The T/QRS ratio was calculated for all the normal fetuses from the maximum magnitudes of the QRS complex and the T wave. Current-arrow maps of the QRS complex (R wave) and T wave were obtained by using the 64-channel system, and the phase differences of the total-current vectors were calculated by using the current-arrow maps, The results showed that the T/QRS ratio had a wide variability of 0.35 for the normal fetuses. However, the magnitude of the prolonged T wave was as weak as the detection limit of the SQUID magnetometer. Although the T/QRS ratios for the fetuses with QT prolongation were within the normal range (

Original languageEnglish
Pages (from-to)377-387
Number of pages11
JournalPhysiological Measurement
Volume22
Issue number2
DOIs
Publication statusPublished - May 2001
Externally publishedYes

Fingerprint

Prenatal Diagnosis
Fetus
SQUIDs
Equipment and Supplies
Magnetometers
Limit of Detection
Reference Values

Keywords

  • Fetal magnetocardiogram
  • Long-QT syndrome
  • QRS ratio
  • T

ASJC Scopus subject areas

  • Biophysics

Cite this

Prenatal diagnosis of QT prolongation by fetal magnetocardiogram - Use of QRS and T-wave current-arrow maps. / Kandori, Akihiko; Miyashita, Tsuyoshi; Tsukada, Keiji; Hosono, Takayoshi; Miyashita, Susumu; Chiba, Yoshihide; Horigome, Hitoshi; Shigemitsu, Sadahiko; Asaka, Mitsuhiro.

In: Physiological Measurement, Vol. 22, No. 2, 05.2001, p. 377-387.

Research output: Contribution to journalArticle

Kandori, A, Miyashita, T, Tsukada, K, Hosono, T, Miyashita, S, Chiba, Y, Horigome, H, Shigemitsu, S & Asaka, M 2001, 'Prenatal diagnosis of QT prolongation by fetal magnetocardiogram - Use of QRS and T-wave current-arrow maps', Physiological Measurement, vol. 22, no. 2, pp. 377-387. https://doi.org/10.1088/0967-3334/22/2/309
Kandori, Akihiko ; Miyashita, Tsuyoshi ; Tsukada, Keiji ; Hosono, Takayoshi ; Miyashita, Susumu ; Chiba, Yoshihide ; Horigome, Hitoshi ; Shigemitsu, Sadahiko ; Asaka, Mitsuhiro. / Prenatal diagnosis of QT prolongation by fetal magnetocardiogram - Use of QRS and T-wave current-arrow maps. In: Physiological Measurement. 2001 ; Vol. 22, No. 2. pp. 377-387.
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