Prefabricated bone graft induced from grafted periosteum for the repair of jaw defects

An experimental study in rabbits

Takaaki Ueno, Toshimasa Kagawa, Nobuhisa Ishida, Joji Fukunaga, Nobuyoshi Mizukawa, Toshio Sugahara, Toshio Yamamoto

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Purpose: The purpose of the study was to determine whether a prefabricated graft of new bone induced from periosteum grafted into muscle was an effective material for the repair of jaw defects. Material and Methods: Artificial mandibular jaw defects in young Japanese rabbits were covered either with free grafted periosteum (n = 5) or a prefabricated graft of newly formed bone induced from periosteum, which was first grafted into the floor of the mouth, and placed as a revascularized muscle-pedicled bone flap (n = 5). Bone formation in jaw defects was examined radiographically and histologically 28 days after grafting into defects. Results: Bone formation was confirmed radiographically and histologically in both groups. However, the free grafted periosteum formed thin bone and fibrous tissue existed between the new and the original bone. In contrast, more active bone formation was observed with the prefabricated graft. This grafted new bone developed further and fused to the mandible. Blood vessels surrounding the new bone were observed histologically. Conclusion: These experimental findings suggested that prefabricated bone grafts induced from periosteum grafts are potentially useful for correction of jaw defects.

Original languageEnglish
Pages (from-to)219-223
Number of pages5
JournalJournal of Cranio-Maxillofacial Surgery
Volume29
Issue number4
Publication statusPublished - 2001

Fingerprint

Periosteum
Jaw
Rabbits
Transplants
Bone and Bones
Osteogenesis
Mouth Floor
Muscles
Surgical Flaps
Mandible
Blood Vessels

ASJC Scopus subject areas

  • Dentistry(all)
  • Otorhinolaryngology
  • Surgery

Cite this

Prefabricated bone graft induced from grafted periosteum for the repair of jaw defects : An experimental study in rabbits. / Ueno, Takaaki; Kagawa, Toshimasa; Ishida, Nobuhisa; Fukunaga, Joji; Mizukawa, Nobuyoshi; Sugahara, Toshio; Yamamoto, Toshio.

In: Journal of Cranio-Maxillofacial Surgery, Vol. 29, No. 4, 2001, p. 219-223.

Research output: Contribution to journalArticle

Ueno, Takaaki ; Kagawa, Toshimasa ; Ishida, Nobuhisa ; Fukunaga, Joji ; Mizukawa, Nobuyoshi ; Sugahara, Toshio ; Yamamoto, Toshio. / Prefabricated bone graft induced from grafted periosteum for the repair of jaw defects : An experimental study in rabbits. In: Journal of Cranio-Maxillofacial Surgery. 2001 ; Vol. 29, No. 4. pp. 219-223.
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