Predictors of vasovagal reactions during preoperative autologous blood donation: a single-institution analysis

Hisakazu Nishimori, Nobuharu Fujii, Keiko Fujii, Tohru Ikeda, Naomi Asano, Hiroaki Ogo, Miwa Yamakawa, Naoe Takagi, Fumio Otsuka, Kazuma Ikeda

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Studies examining risk factors associated with vasovagal reactions (VVRs) during autologous blood donations, especially in younger subjects, have been limited. The aim of the present study was to define risk factors for VVRs during preoperative autologous blood donation in patients, including those younger than 18 years old. We retrospectively analyzed 4192 autologous, preoperative blood donations between 2007 and 2015 at Okayama University Hospital. Eighty-seven (2.08%) of the patients experienced VVRs. VVRs occurred approximately three times as often in patients 0–17 years old (16/320, 5.0%) than in patients 18 years and older (71/3872, 1.8%). In particular, VVRs occurred more frequently in those 10–13 years old, and decreased with older age (P = 0.006). In a univariate analysis, younger age, lower body mass index, lower systolic blood pressure, lower body weight, lower total blood volume, female gender, first-time collection, and higher heart rate were associated with a higher incidence of VVRs. In a multivariate analysis, lower systolic blood pressure (P < 0.001), higher heart rate (P = 0.007), and first-time collection (P = 0.015), remained independent predictors of VVRs. These results emphasize the need for careful attention during blood collection.

Original languageEnglish
Pages (from-to)812-818
Number of pages7
JournalInternational Journal of Hematology
Volume105
Issue number6
DOIs
Publication statusPublished - Jun 1 2017

Fingerprint

Blood Donors
Blood Pressure
Heart Rate
Blood Volume
Body Mass Index
Multivariate Analysis
Body Weight
Incidence

Keywords

  • Autologous blood donation
  • Vasovagal reactions

ASJC Scopus subject areas

  • Hematology

Cite this

Predictors of vasovagal reactions during preoperative autologous blood donation : a single-institution analysis. / Nishimori, Hisakazu; Fujii, Nobuharu; Fujii, Keiko; Ikeda, Tohru; Asano, Naomi; Ogo, Hiroaki; Yamakawa, Miwa; Takagi, Naoe; Otsuka, Fumio; Ikeda, Kazuma.

In: International Journal of Hematology, Vol. 105, No. 6, 01.06.2017, p. 812-818.

Research output: Contribution to journalArticle

@article{6619c20cb7c144ad9f4b32e7837099bd,
title = "Predictors of vasovagal reactions during preoperative autologous blood donation: a single-institution analysis",
abstract = "Studies examining risk factors associated with vasovagal reactions (VVRs) during autologous blood donations, especially in younger subjects, have been limited. The aim of the present study was to define risk factors for VVRs during preoperative autologous blood donation in patients, including those younger than 18 years old. We retrospectively analyzed 4192 autologous, preoperative blood donations between 2007 and 2015 at Okayama University Hospital. Eighty-seven (2.08{\%}) of the patients experienced VVRs. VVRs occurred approximately three times as often in patients 0–17 years old (16/320, 5.0{\%}) than in patients 18 years and older (71/3872, 1.8{\%}). In particular, VVRs occurred more frequently in those 10–13 years old, and decreased with older age (P = 0.006). In a univariate analysis, younger age, lower body mass index, lower systolic blood pressure, lower body weight, lower total blood volume, female gender, first-time collection, and higher heart rate were associated with a higher incidence of VVRs. In a multivariate analysis, lower systolic blood pressure (P < 0.001), higher heart rate (P = 0.007), and first-time collection (P = 0.015), remained independent predictors of VVRs. These results emphasize the need for careful attention during blood collection.",
keywords = "Autologous blood donation, Vasovagal reactions",
author = "Hisakazu Nishimori and Nobuharu Fujii and Keiko Fujii and Tohru Ikeda and Naomi Asano and Hiroaki Ogo and Miwa Yamakawa and Naoe Takagi and Fumio Otsuka and Kazuma Ikeda",
year = "2017",
month = "6",
day = "1",
doi = "10.1007/s12185-017-2204-6",
language = "English",
volume = "105",
pages = "812--818",
journal = "International Journal of Hematology",
issn = "0925-5710",
publisher = "Springer Japan",
number = "6",

}

TY - JOUR

T1 - Predictors of vasovagal reactions during preoperative autologous blood donation

T2 - a single-institution analysis

AU - Nishimori, Hisakazu

AU - Fujii, Nobuharu

AU - Fujii, Keiko

AU - Ikeda, Tohru

AU - Asano, Naomi

AU - Ogo, Hiroaki

AU - Yamakawa, Miwa

AU - Takagi, Naoe

AU - Otsuka, Fumio

AU - Ikeda, Kazuma

PY - 2017/6/1

Y1 - 2017/6/1

N2 - Studies examining risk factors associated with vasovagal reactions (VVRs) during autologous blood donations, especially in younger subjects, have been limited. The aim of the present study was to define risk factors for VVRs during preoperative autologous blood donation in patients, including those younger than 18 years old. We retrospectively analyzed 4192 autologous, preoperative blood donations between 2007 and 2015 at Okayama University Hospital. Eighty-seven (2.08%) of the patients experienced VVRs. VVRs occurred approximately three times as often in patients 0–17 years old (16/320, 5.0%) than in patients 18 years and older (71/3872, 1.8%). In particular, VVRs occurred more frequently in those 10–13 years old, and decreased with older age (P = 0.006). In a univariate analysis, younger age, lower body mass index, lower systolic blood pressure, lower body weight, lower total blood volume, female gender, first-time collection, and higher heart rate were associated with a higher incidence of VVRs. In a multivariate analysis, lower systolic blood pressure (P < 0.001), higher heart rate (P = 0.007), and first-time collection (P = 0.015), remained independent predictors of VVRs. These results emphasize the need for careful attention during blood collection.

AB - Studies examining risk factors associated with vasovagal reactions (VVRs) during autologous blood donations, especially in younger subjects, have been limited. The aim of the present study was to define risk factors for VVRs during preoperative autologous blood donation in patients, including those younger than 18 years old. We retrospectively analyzed 4192 autologous, preoperative blood donations between 2007 and 2015 at Okayama University Hospital. Eighty-seven (2.08%) of the patients experienced VVRs. VVRs occurred approximately three times as often in patients 0–17 years old (16/320, 5.0%) than in patients 18 years and older (71/3872, 1.8%). In particular, VVRs occurred more frequently in those 10–13 years old, and decreased with older age (P = 0.006). In a univariate analysis, younger age, lower body mass index, lower systolic blood pressure, lower body weight, lower total blood volume, female gender, first-time collection, and higher heart rate were associated with a higher incidence of VVRs. In a multivariate analysis, lower systolic blood pressure (P < 0.001), higher heart rate (P = 0.007), and first-time collection (P = 0.015), remained independent predictors of VVRs. These results emphasize the need for careful attention during blood collection.

KW - Autologous blood donation

KW - Vasovagal reactions

UR - http://www.scopus.com/inward/record.url?scp=85014530076&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85014530076&partnerID=8YFLogxK

U2 - 10.1007/s12185-017-2204-6

DO - 10.1007/s12185-017-2204-6

M3 - Article

C2 - 28271415

AN - SCOPUS:85014530076

VL - 105

SP - 812

EP - 818

JO - International Journal of Hematology

JF - International Journal of Hematology

SN - 0925-5710

IS - 6

ER -