Predicting pleural invasion using HRCT and 18F-FDG PET/CT in lung adenocarcinoma with pleural contact

Takashi Tanaka, Takayoshi Shinya, Shuhei Sato, Toshiharu Mitsuhashi, Koichi Ichimura, Junichi Sou, Shinichi Toyooka, Mitsumasa Kaji, Shinichiro Miyoshi, Susumu Kanazawa

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective: To evaluate the relevance of high-resolution computed tomography (HRCT) findings and fluorine-18-fluorodeoxyglucose (18F-FDG) uptake for risk stratification of visceral pleural invasion by lung adenocarcinoma. Methods: The HRCT findings and 18F-FDG uptake for lung adenocarcinomas with pleural contact on CT were retrospectively analyzed in 208 consecutive patients (94 females and 114 males; median age, 69.0 years) between January 2009 and December 2013, with institutional review board approval. The HRCT findings and maximum standardized uptake value (SUVmax) were recorded for each patient. Multivariate logistic regression was used for statistical analysis, and subgroup analysis stratified for whole tumor size ≤3 cm was also performed. Results: Multivariate analysis showed that SUVmax [odds ratio (OR) 1.09, 95 % confidence interval (CI) 1.02–1.16, P = 0.014] and obtuse angle (OR 4.14, 95 % CI 1.97–8.74, P 

Original languageEnglish
Pages (from-to)757-765
Number of pages9
JournalAnnals of Nuclear Medicine
Volume29
Issue number9
DOIs
Publication statusPublished - Jul 5 2015

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Fluorodeoxyglucose F18
Tomography
Odds Ratio
Confidence Intervals
Research Ethics Committees
Multivariate Analysis
Logistic Models
Adenocarcinoma of lung
Neoplasms

Keywords

  • F-FDG
  • HRCT
  • Lung adenocarcinoma
  • PET/CT
  • Visceral pleural invasion

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Predicting pleural invasion using HRCT and 18F-FDG PET/CT in lung adenocarcinoma with pleural contact. / Tanaka, Takashi; Shinya, Takayoshi; Sato, Shuhei; Mitsuhashi, Toshiharu; Ichimura, Koichi; Sou, Junichi; Toyooka, Shinichi; Kaji, Mitsumasa; Miyoshi, Shinichiro; Kanazawa, Susumu.

In: Annals of Nuclear Medicine, Vol. 29, No. 9, 05.07.2015, p. 757-765.

Research output: Contribution to journalArticle

Tanaka, Takashi ; Shinya, Takayoshi ; Sato, Shuhei ; Mitsuhashi, Toshiharu ; Ichimura, Koichi ; Sou, Junichi ; Toyooka, Shinichi ; Kaji, Mitsumasa ; Miyoshi, Shinichiro ; Kanazawa, Susumu. / Predicting pleural invasion using HRCT and 18F-FDG PET/CT in lung adenocarcinoma with pleural contact. In: Annals of Nuclear Medicine. 2015 ; Vol. 29, No. 9. pp. 757-765.
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