Potential roles of arginine-vasotocin in the regulation of aggressive behavior in the mudskipper (Periophthalmus modestus)

Nao Kagawa, Yudai Nishiyama, Kanoko Kato, Hideya Takahashi, Yasuhisa Kobayashi, Hirotaka Sakamoto, Tatsuya Sakamoto

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The hypothalamic hormones, arginine-vasotocin (VT) and isotocin (IT), play central roles in osmoregulation and in the regulation of social behaviors including aggressive behavior in many vertebrates including fish. Here, we examined whether these hormones are associated with aggressive behavior in the mudskipper (Periophthalmus modestus). The mudskipper is an amphibious fish, which lives in the brackish water of river mouths and displays unique aggressive behavior. Upon introduction to each other in an experimental tank with aquatic and terrestrial areas, a pair of males can be classified as aggressive dominant or submissive subordinate based on the frequency of their aggressive acts, which is significantly higher in dominant male. Additionally, the length of stay in terrestrial area of dominant was longer than that of the subordinate. The latter remained in aquatic area almost throughout the period of behavioral observation. The expression of brain VT mRNA was significantly higher in subordinate than in dominant, whereas neither IT mRNA expression nor plasma cortisol level differed between subordinate and dominant male. On the other hand, an intracerebroventricular injection of VT increased aggressive behaviors in mudskippers. In addition to known roles of VT in mediation of aggressive behavior, these results may shed light on the role of endogenous VT toward water migration in submissive mudskippers. The amphibious fish is a valuable experimental model to observe the relationship between effects of central VT on the osmoregulation and social behavioral regulation in vertebrates.

Original languageEnglish
Pages (from-to)257-263
Number of pages7
JournalGeneral and Comparative Endocrinology
Volume194
DOIs
Publication statusPublished - Dec 1 2013

Fingerprint

vasotocin
arginine vasotocin
Vasotocin
aggression
osmoregulation
Osmoregulation
Fishes
fish
hypothalamic hormones
vertebrates
Vertebrates
Hypothalamic Hormones
Messenger RNA
social behavior
brackish water
Social Behavior
cortisol
mouth
Rivers
hormones

Keywords

  • Aggressive behavior
  • Amphibious fish
  • Mudskipper
  • Submissive behavior
  • Vasotocin

ASJC Scopus subject areas

  • Endocrinology

Cite this

Potential roles of arginine-vasotocin in the regulation of aggressive behavior in the mudskipper (Periophthalmus modestus). / Kagawa, Nao; Nishiyama, Yudai; Kato, Kanoko; Takahashi, Hideya; Kobayashi, Yasuhisa; Sakamoto, Hirotaka; Sakamoto, Tatsuya.

In: General and Comparative Endocrinology, Vol. 194, 01.12.2013, p. 257-263.

Research output: Contribution to journalArticle

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