Potency of insect-specific scorpion toxins on mosquito control using Bacillus thuringiensis Cry4Aa

Riku Matsumoto, Yoshitaka Shimizu, Mohammad Tofazzal Hossain Howlader, Maho Namba, Aya Iwamoto, Hiroshi Sakai, Tohru Hayakawa

Research output: Contribution to journalArticle

4 Citations (Scopus)


Two insect-specific scorpion toxins, BjαIT and AahITwere produced as alkali-soluble protein inclusions in Escherichia coli. The inclusion bodies themselves exhibited no toxicity against Culex pipiens larvae. However, coadministration with Cry4Aa toxin enhanced the mosquitocidal activity by 2-3 fold. Insect-specific scorpion toxins can be good supplements for Cry toxin-based bioinsecticides.

Original languageEnglish
Pages (from-to)680-683
Number of pages4
JournalJournal of Bioscience and Bioengineering
Issue number6
Publication statusPublished - Jun 2014



  • AahIT
  • Bacillus thuringiensis
  • BjαIT
  • Cry4Aa
  • Culex pipiens
  • Mosquito control
  • Scorpion toxins

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

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