Postoperative mechanical bowel obstruction after pharyngolaryngectomy for hypopharyngeal cancer: Retrospective analysis using a Japanese inpatient database

Sayaka Suzuki, Hideo Yasunaga, Hiroki Matsui, Kiyohide Fushimi, Mizuo Ando, Tatsuya Yamasoba

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Background: Data have been limited on donor-site mechanical bowel obstruction after pharyngolaryngectomy with free jejunum graft reconstruction. Methods: Using a nationwide Japanese inpatient database, we extracted data on patients who underwent pharyngolaryngectomy for hypopharyngeal cancer between July 2007 and March 2014. A Cox proportional hazard model was used to determine the association between background characteristics and the occurrence of mechanical bowel obstruction. Results: Among the 3320 eligible patients from 332 hospitals, 108 patients (3.3%) developed mechanical bowel obstruction after a median 88 (interquartile range 26-217) postoperative days. Multivariable Cox regression analysis revealed that older age (≥60 years old) was independently associated with an increased risk of mechanical bowel obstruction, whereas sex, body mass index [BMI], smoking status, comorbidity at admission, blood transfusion, history of surgery, and hospital type were not. Conclusion: In pharyngolaryngectomy, careful attention should be paid to the risk of abdominal complications and, thus, to the graft choice, especially in elderly patients.

Original languageEnglish
Pages (from-to)1548-1554
Number of pages7
JournalHead and Neck
Volume40
Issue number7
DOIs
Publication statusPublished - Jul 2018
Externally publishedYes

Keywords

  • donor-site abdominal complications
  • free jejunal flap reconstruction
  • Japanese national inpatient database
  • pharyngolaryngectomy
  • risk factors

ASJC Scopus subject areas

  • Otorhinolaryngology

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