Post-monsoon waterlogging-associated upsurge of cholera cases in and around Kolkata metropolis, 2015

Asish K. Mukhopadhyay, Alok K. Deb, Goutam Chowdhury, Falguni Debnath, Prosenjit Samanta, Rudra Narayan Saha, Byomkesh Manna, Mihir K. Bhattacharya, Dharitri Datta, Keinosuke Okamoto, Uchhal K. Bhadra, Shanta Dutta

Research output: Contribution to journalArticle

Abstract

The Infectious Diseases and Beliaghata General Hospital, Kolkata, India witnessed a sudden increase in admissions of diarrhoea cases during the first 2 weeks of August 2015 following heavy rainfall. This prompted us to investigate the event. Cases were recruited through hospital-based surveillance along with the collection of socio-demographic characteristics and clinical profile using a structured questionnaire. Stool specimens were tested at bacteriological laboratory of the National Institute of Cholera and Enteric Diseases (NICED), Kolkata. Admission of 3003 diarrhoea cases, clearly indicated occurrence of outbreak in Kolkata municipal area as it was more than two standard deviation of the mean number (911; s.d. = 111) of diarrhoea admissions during the same period in previous 7 years. Out of 164 recruited cases, 25% were under-5 children. Organisms were isolated from 80 (49%) stool specimens. Vibrio cholerae O1 was isolated from 50 patients. Twenty-eight patients had this organism as the sole pathogen. Among 14 infants, five had cholera. All V. cholerae O1 isolates were resistant to nalidixic acid, followed by co-trimoxazole (96%), streptomycin (92%), but sensitive to fluroquinolones. We confirmed the occurrence of a cholera outbreak in Kolkata during August 2015 due to V. cholerae O1 infection, where infants were affected.

Original languageEnglish
Pages (from-to)e167
JournalEpidemiology and infection
Volume147
DOIs
Publication statusPublished - Jan 1 2019
Externally publishedYes

Fingerprint

Vibrio cholerae O1
Cholera
Diarrhea
Disease Outbreaks
Nalidixic Acid
Sulfamethoxazole Drug Combination Trimethoprim
Streptomycin
General Hospitals
Communicable Diseases
India
Demography
Infection

Keywords

  • Cholera
  • diarrhoea
  • Vibrio cholerae

ASJC Scopus subject areas

  • Epidemiology
  • Infectious Diseases

Cite this

Mukhopadhyay, A. K., Deb, A. K., Chowdhury, G., Debnath, F., Samanta, P., Saha, R. N., ... Dutta, S. (2019). Post-monsoon waterlogging-associated upsurge of cholera cases in and around Kolkata metropolis, 2015. Epidemiology and infection, 147, e167. https://doi.org/10.1017/S0950268819000529

Post-monsoon waterlogging-associated upsurge of cholera cases in and around Kolkata metropolis, 2015. / Mukhopadhyay, Asish K.; Deb, Alok K.; Chowdhury, Goutam; Debnath, Falguni; Samanta, Prosenjit; Saha, Rudra Narayan; Manna, Byomkesh; Bhattacharya, Mihir K.; Datta, Dharitri; Okamoto, Keinosuke; Bhadra, Uchhal K.; Dutta, Shanta.

In: Epidemiology and infection, Vol. 147, 01.01.2019, p. e167.

Research output: Contribution to journalArticle

Mukhopadhyay, AK, Deb, AK, Chowdhury, G, Debnath, F, Samanta, P, Saha, RN, Manna, B, Bhattacharya, MK, Datta, D, Okamoto, K, Bhadra, UK & Dutta, S 2019, 'Post-monsoon waterlogging-associated upsurge of cholera cases in and around Kolkata metropolis, 2015', Epidemiology and infection, vol. 147, pp. e167. https://doi.org/10.1017/S0950268819000529
Mukhopadhyay, Asish K. ; Deb, Alok K. ; Chowdhury, Goutam ; Debnath, Falguni ; Samanta, Prosenjit ; Saha, Rudra Narayan ; Manna, Byomkesh ; Bhattacharya, Mihir K. ; Datta, Dharitri ; Okamoto, Keinosuke ; Bhadra, Uchhal K. ; Dutta, Shanta. / Post-monsoon waterlogging-associated upsurge of cholera cases in and around Kolkata metropolis, 2015. In: Epidemiology and infection. 2019 ; Vol. 147. pp. e167.
@article{a1e29b2e702348d3b67b708bfd8a1e59,
title = "Post-monsoon waterlogging-associated upsurge of cholera cases in and around Kolkata metropolis, 2015",
abstract = "The Infectious Diseases and Beliaghata General Hospital, Kolkata, India witnessed a sudden increase in admissions of diarrhoea cases during the first 2 weeks of August 2015 following heavy rainfall. This prompted us to investigate the event. Cases were recruited through hospital-based surveillance along with the collection of socio-demographic characteristics and clinical profile using a structured questionnaire. Stool specimens were tested at bacteriological laboratory of the National Institute of Cholera and Enteric Diseases (NICED), Kolkata. Admission of 3003 diarrhoea cases, clearly indicated occurrence of outbreak in Kolkata municipal area as it was more than two standard deviation of the mean number (911; s.d. = 111) of diarrhoea admissions during the same period in previous 7 years. Out of 164 recruited cases, 25{\%} were under-5 children. Organisms were isolated from 80 (49{\%}) stool specimens. Vibrio cholerae O1 was isolated from 50 patients. Twenty-eight patients had this organism as the sole pathogen. Among 14 infants, five had cholera. All V. cholerae O1 isolates were resistant to nalidixic acid, followed by co-trimoxazole (96{\%}), streptomycin (92{\%}), but sensitive to fluroquinolones. We confirmed the occurrence of a cholera outbreak in Kolkata during August 2015 due to V. cholerae O1 infection, where infants were affected.",
keywords = "Cholera, diarrhoea, Vibrio cholerae",
author = "Mukhopadhyay, {Asish K.} and Deb, {Alok K.} and Goutam Chowdhury and Falguni Debnath and Prosenjit Samanta and Saha, {Rudra Narayan} and Byomkesh Manna and Bhattacharya, {Mihir K.} and Dharitri Datta and Keinosuke Okamoto and Bhadra, {Uchhal K.} and Shanta Dutta",
year = "2019",
month = "1",
day = "1",
doi = "10.1017/S0950268819000529",
language = "English",
volume = "147",
pages = "e167",
journal = "Epidemiology and Infection",
issn = "0950-2688",
publisher = "Cambridge University Press",

}

TY - JOUR

T1 - Post-monsoon waterlogging-associated upsurge of cholera cases in and around Kolkata metropolis, 2015

AU - Mukhopadhyay, Asish K.

AU - Deb, Alok K.

AU - Chowdhury, Goutam

AU - Debnath, Falguni

AU - Samanta, Prosenjit

AU - Saha, Rudra Narayan

AU - Manna, Byomkesh

AU - Bhattacharya, Mihir K.

AU - Datta, Dharitri

AU - Okamoto, Keinosuke

AU - Bhadra, Uchhal K.

AU - Dutta, Shanta

PY - 2019/1/1

Y1 - 2019/1/1

N2 - The Infectious Diseases and Beliaghata General Hospital, Kolkata, India witnessed a sudden increase in admissions of diarrhoea cases during the first 2 weeks of August 2015 following heavy rainfall. This prompted us to investigate the event. Cases were recruited through hospital-based surveillance along with the collection of socio-demographic characteristics and clinical profile using a structured questionnaire. Stool specimens were tested at bacteriological laboratory of the National Institute of Cholera and Enteric Diseases (NICED), Kolkata. Admission of 3003 diarrhoea cases, clearly indicated occurrence of outbreak in Kolkata municipal area as it was more than two standard deviation of the mean number (911; s.d. = 111) of diarrhoea admissions during the same period in previous 7 years. Out of 164 recruited cases, 25% were under-5 children. Organisms were isolated from 80 (49%) stool specimens. Vibrio cholerae O1 was isolated from 50 patients. Twenty-eight patients had this organism as the sole pathogen. Among 14 infants, five had cholera. All V. cholerae O1 isolates were resistant to nalidixic acid, followed by co-trimoxazole (96%), streptomycin (92%), but sensitive to fluroquinolones. We confirmed the occurrence of a cholera outbreak in Kolkata during August 2015 due to V. cholerae O1 infection, where infants were affected.

AB - The Infectious Diseases and Beliaghata General Hospital, Kolkata, India witnessed a sudden increase in admissions of diarrhoea cases during the first 2 weeks of August 2015 following heavy rainfall. This prompted us to investigate the event. Cases were recruited through hospital-based surveillance along with the collection of socio-demographic characteristics and clinical profile using a structured questionnaire. Stool specimens were tested at bacteriological laboratory of the National Institute of Cholera and Enteric Diseases (NICED), Kolkata. Admission of 3003 diarrhoea cases, clearly indicated occurrence of outbreak in Kolkata municipal area as it was more than two standard deviation of the mean number (911; s.d. = 111) of diarrhoea admissions during the same period in previous 7 years. Out of 164 recruited cases, 25% were under-5 children. Organisms were isolated from 80 (49%) stool specimens. Vibrio cholerae O1 was isolated from 50 patients. Twenty-eight patients had this organism as the sole pathogen. Among 14 infants, five had cholera. All V. cholerae O1 isolates were resistant to nalidixic acid, followed by co-trimoxazole (96%), streptomycin (92%), but sensitive to fluroquinolones. We confirmed the occurrence of a cholera outbreak in Kolkata during August 2015 due to V. cholerae O1 infection, where infants were affected.

KW - Cholera

KW - diarrhoea

KW - Vibrio cholerae

UR - http://www.scopus.com/inward/record.url?scp=85065638673&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85065638673&partnerID=8YFLogxK

U2 - 10.1017/S0950268819000529

DO - 10.1017/S0950268819000529

M3 - Article

C2 - 31063116

AN - SCOPUS:85065638673

VL - 147

SP - e167

JO - Epidemiology and Infection

JF - Epidemiology and Infection

SN - 0950-2688

ER -