Possible role of insulin-like factor 3 in the bovine corpus luteum

Misato Abe; Takuo Hojo; Keisuke Kozai; Kiyoshi Okuda

doi:10.1292/jvms.12-0423

Possible role of insulin-like factor 3 in the bovine corpus luteum

Misato Abe, Takuo Hojo, Keisuke Kozai, Kiyoshi Okuda

Faculty of Agriculture

Research output: Contribution to journal › Article

1 Citation (Scopus)

Abstract

Insulin-like factor 3 (INSL3) is a local regulator in mammalian gonads, but little is known of its function in bovine corpus luteum (CL). Here, we show that RXFP2 protein, the receptor of INSL3, was expressed throughout the estrous cycle and significantly high at the early luteal stage compared to the regressed luteal stage. INSL3 stimulated progesterone secretion, but not prostaglandin F2α and viability in cultured luteal cells. Together, these results suggest that INSL3 plays a luteotropic role as a local regulator in the bovine CL.

Original language	English
Pages (from-to)	629-632
Number of pages	4
Journal	Journal of Veterinary Medical Science
Volume	75
Issue number	5
DOIs	https://doi.org/10.1292/jvms.12-0423
Publication status	Published - 2013

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Keywords

Bovine
Corpus luteum
Estrous cycle
Insulin-like factor 3
Insulin-like factor 3 receptor

ASJC Scopus subject areas

veterinary(all)

Cite this

Abe, M., Hojo, T., Kozai, K., & Okuda, K. (2013). Possible role of insulin-like factor 3 in the bovine corpus luteum. Journal of Veterinary Medical Science, 75(5), 629-632. https://doi.org/10.1292/jvms.12-0423

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10.1292/jvms.12-0423