Possible Anti-tumor Promoting Properties of Edible Plants from Thailand, and Identification of an Active Constituent, Cardamonin, of Boesenbergia pandurata

Akira Murakami, Akira Kondo, Yoshimasa Nakamura, Hajime Ohigashi, Koichi Koshimizu

Research output: Contribution to journalArticlepeer-review

58 Citations (Scopus)

Abstract

Possible anti-tumor promoting properties of a total of 40 methanol extracts from Thai edible plants, including 5 non-edible species, were estimated in vitro by an inhibition test of tumor promoter-induced Epstein-Barr virus (EBV) activation. Fourteen species (35% of the total) were found to be strongly active. In addition, cardamonin (2′,4′-dihydroxy-6′-methoxychalcone) was identified as a potently active constituent (IC50 = 3.1 μm) of Boesenbergia pandurata (Zingiberaceae), suggesting it to be an effective anti-tumor promoter.

Original languageEnglish
Pages (from-to)1971-1973
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume57
Issue number11
DOIs
Publication statusPublished - 1993
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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