Possible anti-tumor promoting properties of a total of 40 methanol extracts from Thai edible plants, including 5 non-edible species, were estimated in vitro by an inhibition test of tumor promoter-induced Epstein-Barr virus (EBV) activation. Fourteen species (35% of the total) were found to be strongly active. In addition, cardamonin (2′,4′-dihydroxy-6′-methoxychalcone) was identified as a potently active constituent (IC50 = 3.1 μm) of Boesenbergia pandurata (Zingiberaceae), suggesting it to be an effective anti-tumor promoter.
ASJC Scopus subject areas
- Analytical Chemistry
- Applied Microbiology and Biotechnology
- Molecular Biology
- Organic Chemistry