Possibility of odontoblasts activity up-regulation due to orthodontic mechanical stress in mice

Keisuke Nakano, Rina Muraoka, Mihoko Tomida, Sachiko Matsuura, Norimasa Okafuji, Chong Huat Siar, Toshiyuki Kawakami

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Abstract: Using Waldo's method in mice, we examined the immunohistochemical expression of Runx2 and alkaline phosphatase (ALP) appearing in dental pulp cells, especially in odontoblasts, just after receiving experimental orthodontic mechanical stress, using Waldo's method in mice. The examination results demonstrated that some dental root pulp cells, especially some odontoblasts, expressed the Runx2 and ALP in a comparatively short time after receiving the stress. The results suggest that the stress may cause odontoblast activity up- regulation.

Original languageEnglish
Pages (from-to)13-16
Number of pages4
JournalJournal of Hard Tissue Biology
Volume19
Issue number1
DOIs
Publication statusPublished - Jul 19 2010
Externally publishedYes

Keywords

  • Alkaline phosphatase (alp)
  • Dental pulp cells
  • Mechanical stress
  • Odontoblasts
  • Orthodontics
  • Runx2
  • Up-regulation

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biochemistry
  • Biomaterials
  • Orthopedics and Sports Medicine
  • Dentistry(all)
  • Cell Biology

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