Positive gallium-67 and thallium-201 scans in thymic rebound after chemotherapy for lymphoma

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

It is a diagnostic problem to distinguish thymic rebound or rebound thymic hyperplasia from thymic malignancy, but it is frequently made more difficult because most patients have had previous malignancies. Recently we evaluated a six-year-old girl with thymic rebound after chemotherapy for lymphoma, by both gallium-67 and thallium-201 scans. On gallium-67 scan, intensive uptake was seen in the anterior mediastinum. CT revealed a triangular-shaped, homogeneous mass in the anterior mediastinum. On early scan of thallium-201 study, slight accumulation was seen in the anterior mediastinum and was enhanced in delayed scans. Considering the clinical state and imaging results, thymic rebound after chemotherapy was the most likely diagnosis, and follow-up observation was done without therapy. During the course, there were no signs of relapse. Some reports have described both positive and negative thallium-201 accumulation in thymic rebound. Although more experience with similar cases is necessary, it is likely that thallium-201 also tends to accumulate in thymic rebound as well as gallium-67.

Original languageEnglish
Pages (from-to)161-163
Number of pages3
JournalAnnals of Nuclear Medicine
Volume20
Issue number2
DOIs
Publication statusPublished - 2006

Fingerprint

Gallium
Thallium
Lymphoma
Mediastinum
Drug Therapy
Thymus Hyperplasia
Neoplasms
Observation
Recurrence
Therapeutics

Keywords

  • Gallium-67
  • Thallium-201
  • Thymic rebound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Positive gallium-67 and thallium-201 scans in thymic rebound after chemotherapy for lymphoma. / Akaki, Shiro; Shinya, Takayoshi; Sato, Shuhei; Kuroda, Masahiro; Kanazawa, Susumu.

In: Annals of Nuclear Medicine, Vol. 20, No. 2, 2006, p. 161-163.

Research output: Contribution to journalArticle

@article{fd2e2f4fb5fc499bb38ff7276053ac60,
title = "Positive gallium-67 and thallium-201 scans in thymic rebound after chemotherapy for lymphoma",
abstract = "It is a diagnostic problem to distinguish thymic rebound or rebound thymic hyperplasia from thymic malignancy, but it is frequently made more difficult because most patients have had previous malignancies. Recently we evaluated a six-year-old girl with thymic rebound after chemotherapy for lymphoma, by both gallium-67 and thallium-201 scans. On gallium-67 scan, intensive uptake was seen in the anterior mediastinum. CT revealed a triangular-shaped, homogeneous mass in the anterior mediastinum. On early scan of thallium-201 study, slight accumulation was seen in the anterior mediastinum and was enhanced in delayed scans. Considering the clinical state and imaging results, thymic rebound after chemotherapy was the most likely diagnosis, and follow-up observation was done without therapy. During the course, there were no signs of relapse. Some reports have described both positive and negative thallium-201 accumulation in thymic rebound. Although more experience with similar cases is necessary, it is likely that thallium-201 also tends to accumulate in thymic rebound as well as gallium-67.",
keywords = "Gallium-67, Thallium-201, Thymic rebound",
author = "Shiro Akaki and Takayoshi Shinya and Shuhei Sato and Masahiro Kuroda and Susumu Kanazawa",
year = "2006",
doi = "10.1007/BF02985630",
language = "English",
volume = "20",
pages = "161--163",
journal = "Annals of Nuclear Medicine",
issn = "0914-7187",
publisher = "Springer Japan",
number = "2",

}

TY - JOUR

T1 - Positive gallium-67 and thallium-201 scans in thymic rebound after chemotherapy for lymphoma

AU - Akaki, Shiro

AU - Shinya, Takayoshi

AU - Sato, Shuhei

AU - Kuroda, Masahiro

AU - Kanazawa, Susumu

PY - 2006

Y1 - 2006

N2 - It is a diagnostic problem to distinguish thymic rebound or rebound thymic hyperplasia from thymic malignancy, but it is frequently made more difficult because most patients have had previous malignancies. Recently we evaluated a six-year-old girl with thymic rebound after chemotherapy for lymphoma, by both gallium-67 and thallium-201 scans. On gallium-67 scan, intensive uptake was seen in the anterior mediastinum. CT revealed a triangular-shaped, homogeneous mass in the anterior mediastinum. On early scan of thallium-201 study, slight accumulation was seen in the anterior mediastinum and was enhanced in delayed scans. Considering the clinical state and imaging results, thymic rebound after chemotherapy was the most likely diagnosis, and follow-up observation was done without therapy. During the course, there were no signs of relapse. Some reports have described both positive and negative thallium-201 accumulation in thymic rebound. Although more experience with similar cases is necessary, it is likely that thallium-201 also tends to accumulate in thymic rebound as well as gallium-67.

AB - It is a diagnostic problem to distinguish thymic rebound or rebound thymic hyperplasia from thymic malignancy, but it is frequently made more difficult because most patients have had previous malignancies. Recently we evaluated a six-year-old girl with thymic rebound after chemotherapy for lymphoma, by both gallium-67 and thallium-201 scans. On gallium-67 scan, intensive uptake was seen in the anterior mediastinum. CT revealed a triangular-shaped, homogeneous mass in the anterior mediastinum. On early scan of thallium-201 study, slight accumulation was seen in the anterior mediastinum and was enhanced in delayed scans. Considering the clinical state and imaging results, thymic rebound after chemotherapy was the most likely diagnosis, and follow-up observation was done without therapy. During the course, there were no signs of relapse. Some reports have described both positive and negative thallium-201 accumulation in thymic rebound. Although more experience with similar cases is necessary, it is likely that thallium-201 also tends to accumulate in thymic rebound as well as gallium-67.

KW - Gallium-67

KW - Thallium-201

KW - Thymic rebound

UR - http://www.scopus.com/inward/record.url?scp=33645083990&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645083990&partnerID=8YFLogxK

U2 - 10.1007/BF02985630

DO - 10.1007/BF02985630

M3 - Article

VL - 20

SP - 161

EP - 163

JO - Annals of Nuclear Medicine

JF - Annals of Nuclear Medicine

SN - 0914-7187

IS - 2

ER -