TY - JOUR
T1 - Portal/splenic vein thrombosis following splenectomy in gastric cancer surgery
AU - Kagawa, Shunsuke
AU - Uno, Futoshi
AU - Gochi, Akira
AU - Naomoto, Yoshio
AU - Fujiwara, Toshiyoshi
PY - 2010/10
Y1 - 2010/10
N2 - Although splenectomy is often performed along with en bloc node dissection in gastric cancer surgery, portal/splenic vein thrombosis (PSVT) has been rarely reported. We recently encountered a case of PSVT after a splenectomy was performed during gastric cancer surgery. A 53-year-old woman underwent total gastrectomy, splenectomy, and en bloc regional lymph node dissection for gastric cancer. An uneventful postoperative course ended with abrupt development of a fever and general fatigue. Laboratory tests showed elevated levels of liver transaminases and fibrinogen degenerative products. Contrast-enhanced computed tomography revealed splenic vein thrombosis and partial liver infarction. Immediate anticoagulant treatment resulted in clinical improvement and partial thrombolysis in 2 months. PSVT after splenectomy in haematological disorders has been recognized as a possibly lethal complication. However, it has been underappreciated in cases of splenectomy for gastric cancer. The present case demonstrates the importance of considering PSVT as a possible complication of splenectomy in gastric cancer surgery.
AB - Although splenectomy is often performed along with en bloc node dissection in gastric cancer surgery, portal/splenic vein thrombosis (PSVT) has been rarely reported. We recently encountered a case of PSVT after a splenectomy was performed during gastric cancer surgery. A 53-year-old woman underwent total gastrectomy, splenectomy, and en bloc regional lymph node dissection for gastric cancer. An uneventful postoperative course ended with abrupt development of a fever and general fatigue. Laboratory tests showed elevated levels of liver transaminases and fibrinogen degenerative products. Contrast-enhanced computed tomography revealed splenic vein thrombosis and partial liver infarction. Immediate anticoagulant treatment resulted in clinical improvement and partial thrombolysis in 2 months. PSVT after splenectomy in haematological disorders has been recognized as a possibly lethal complication. However, it has been underappreciated in cases of splenectomy for gastric cancer. The present case demonstrates the importance of considering PSVT as a possible complication of splenectomy in gastric cancer surgery.
KW - gastric cancer
KW - portal vein thrombosis
KW - splenectomy
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U2 - 10.1016/S1015-9584(11)60009-2
DO - 10.1016/S1015-9584(11)60009-2
M3 - Article
C2 - 21377109
AN - SCOPUS:79952392140
SN - 1015-9584
VL - 33
SP - 208
EP - 211
JO - Asian Journal of Surgery
JF - Asian Journal of Surgery
IS - 4
ER -
